Abstract 3582: Procedural Duration Impacts Clinical Outcome Following Intra-arterial Stroke Therapy

• Published in: Stroke (1970) 2012-02, Vol.43 (suppl_1)
• Main Authors: Leslie-Mazwi, Thabele M, Chandra, Ronil V, Mehta, Brijesh P, Oh, Daniel C, Chaudhry, Zeshan A, Hirsch, Joshua A, Yoo, Albert J
• Format: Article
• Language: English
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/str.43.suppl_1.A3582

Abstract only Background: Recanalization rates of large vessel occlusions (LVO) are higher with intra-arterial therapy (IAT) than with intravenous tPA. However, there are often time delays to IAT. Multiple pre- and intra-hospital factors impact on time from last seen well (LSW) to recanalization. We sought to compare standard time intervals prior to and during IAT to assess whether there is a differential influence on outcome in LVO. Methods: We analyzed our prospective observational IAT database for patients with anterior circulation stroke undergoing IAT between February 2005 and November 2010. Times of LSW, imaging, groin puncture and recanalization were collected and analyzed. Functional outcome was assessed with 3 month modified Rankin scale (mRS), and was trichotomized into mild (mRS 0-2), moderate (mRS 3) and severe disability (mRS 4-6). Results: Of 174 patients, 50% were female. Mean age was 63.7 years, median NIHSS 17. TICI 2-3 recanalization was strongly associated with improved outcome (p