Abstract TP408: Temporal Relationship of AF and Oral Anticoagulation to Major Bleeding Events in Patients with Cardiovascular Implantable Electronic Devices

Abstract only Introduction: After diagnosis of atrial fibrillation (AF), oral anticoagulation (OAC) is taken daily and may increase risk of bleeding, even during AF-free periods. We explored temporal discordance between AF and major bleeding events (MBE) in patients with cardiovascular implantable e...

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Bibliographic Details
Published in:Stroke (1970) 2017-02, Vol.48 (suppl_1)
Main Authors: Askari, Mariam, Zielger, Paul D, Schmitt, Susan K, Fan, Jun, Ullal, Aditya J, Turakhia, Mintu P
Format: Article
Language:English
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Summary:Abstract only Introduction: After diagnosis of atrial fibrillation (AF), oral anticoagulation (OAC) is taken daily and may increase risk of bleeding, even during AF-free periods. We explored temporal discordance between AF and major bleeding events (MBE) in patients with cardiovascular implantable electronic devices (CIED). Methods: We linked Veterans Administration (VA) and Medicare data to CIED remote monitoring data. Analyses were restricted to Medtronic cardiac rhythm devices with atrial leads, which provide a daily, continuous measure of AF burden. We identified the earliest date of monitoring and searched for a subsequent MBE (including but not limited to intracranial hemorrhaging, gastrointestinal bleeds, and vascular bleeds) from 2004 to 2015. We restricted analysis to patients with
ISSN:0039-2499
1524-4628
DOI:10.1161/str.48.suppl_1.tp408