Abstract WMP99: Hematoma Retraction in Spontaneous Intracerebral Hemorrhage: Frequency, Functional Significance and Relation to Perihematomal Edema

Abstract only Background: The natural history of spontaneous intracerebral hematomas (ICH) is for variable degree of early hematoma retraction (HR), which may determine perihematomal brain edema (PHE), but such inter-relationships have not been rigorously studied. Methods: A pooled analysis of 760 c...

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Bibliographic Details
Published in:Stroke (1970) 2017-02, Vol.48 (suppl_1)
Main Authors: Ziai, Wendy, Anderson, Craig, Parry-Jones, Adrian, Hurford, Robert, Yenokyan, Gayane, Murthy, Santosh, Mcbee, Nichol, Dlugash, Rachel, Awad, Issam, Hanley, Daniel F
Format: Article
Language:English
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Summary:Abstract only Background: The natural history of spontaneous intracerebral hematomas (ICH) is for variable degree of early hematoma retraction (HR), which may determine perihematomal brain edema (PHE), but such inter-relationships have not been rigorously studied. Methods: A pooled analysis of 760 computed tomography (CT) scans within 24±12 hours and 1197 CT scans within 72±12 hours of diagnostic CT (0-6 hours from symptom onset), from non-surgical ICH patients included in the Virtual International Stroke Trials Archive (VISTA), and INTERACT I, CLEAR III and MISTIE II clinical trials. Multivariable logistic regression was used to assess independent associations of HR and good 90-day functional outcome (modified Rankin scale [mRS]
ISSN:0039-2499
1524-4628
DOI:10.1161/str.48.suppl_1.wmp99