Abstract TMP2: Reduction of Time to Endovascular Treatment and Improved Outcomes After Ischemic Stroke in Routine Clinical Practice: Comparison of the MR CLEAN Registry First and Second Cohorts

Abstract only Introduction: Outcomes after endovascular treatment (EVT) for acute ischemic stroke are highly time dependent, but whether active reduction of time to treatment leads to better outcome has not been demonstrated. We compared data of the two subsequent MR CLEAN Registry cohorts, comprisi...

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Published in:Stroke (1970) 2020-02, Vol.51 (Suppl_1)
Main Authors: Compagne, Kars C, Kappelhof, Manon, Goldhoorn, Robert-Jan B, Majoie, Charles B, Roos, Yvo B, van Zwam, Wim H, van Oostenbrugge, Robert J, Boiten, Jelis, Lycklama à Nijeholt, Geert J, den Hertog, Heleen, Gerrits, Dick, Sturm, Emiel J, Brouwers, Paul J, van Walderveen, Marianne A, Wermer, Marieke J, Boogaarts, Hieronymus D, van Dijk, Ewoud J, van Hasselt, Boudewijn A, Fransen, Puck, de Kort, Paul L, van Tuijl, Julia, Peluso, Jo P, de Bruijn, Sebastiaan F, van Dijk, Lukas C, Schonewille, Wouter J, Vos, Jan Albert, Uyttenboogaart, Maarten, Bokkers, Reinoud P, Martens, Jasper M, Hofmeijer, Jeannette, van der Worp, Bart, Lo, Rob, Dippel, Diederik W, van der Lugt, Aad
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Language:English
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Summary:Abstract only Introduction: Outcomes after endovascular treatment (EVT) for acute ischemic stroke are highly time dependent, but whether active reduction of time to treatment leads to better outcome has not been demonstrated. We compared data of the two subsequent MR CLEAN Registry cohorts, comprising all patients in the Netherlands who had EVT for acute ischemic stroke from 2014-2017, for a trend in time to treatment and its association with outcome. Methods: We compared workflow, successful reperfusion (eTICI 2B-3), NIHSS at 24h, functional outcome (mRS) at 90 days, occurrence of symptomatic intracranial hemorrhage (sICH) and mortality in patients with ischemic stroke and a proximal intracranial occlusion in the anterior circulation included in the second cohort of the Registry (June 2016-November 2017; n = 1779) to those in patients included in the first cohort (March 2014-June 2016; n = 1526) using logistic regression. Results: Baseline NIHSS was 16 in both cohorts. Times from onset-to-groin and onset-to-reperfusion were shorter in the second cohort than in the first (185 versus 210 minutes; p
ISSN:0039-2499
1524-4628
DOI:10.1161/str.51.suppl_1.TMP2