Abstract TP315: Initial Stroke Severity and Reperfusion Treatment in Latin-America. Findings From the Lase Registry

• Published in: Stroke (1970) 2020-02, Vol.51 (Suppl_1)
• Main Authors: Flores, Alan, Barboza, Miguel, Serrano, Fabiola, Lavados, Pablo, Fernando, Gongora, Amaya, Pablo, Pujol, Virginia, Ameriso, Sebastián, Lopez-Ruiz, Minerva, Bayona, Hernan, Ecos, Rosa Lizbeth, Mernes, Ricardo, Roa, Luis, Ochoa, Marco, Ruiz, Angelica, Fernandez, Hubert, Castillo, Alejandro, Zapata, Carlos, Morelos, Eugenia, Reyes, Abraham, León, Carolina, Arauz, Antonio
• Format: Article
• Language: English
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/str.51.suppl_1.TP315

Abstract only Information about clinical outcome and reperfusion treatment in Latin-America is not widely known. Our aim was to determine this association and other clinical factors according to the initial clinical severity in functional outcome in the population from the Latin-America Stroke Registry (LASE). Methods: Data were collected prospectively from consecutive patients admitted from January 2012-January 2017 in 20 Latin-American centers. The initial clinical severity was stratified according to the baseline NIHSS; 0-3 minor, 4-7 mild, 8-14 moderate, and ≥15 severe. Clinical outcome was defined by mRS at 3 months, dichotomized in good (0-2) and poor (3-6) groups for univariate and logistic multivariate analysis. Results: Among 5381 patients, 823(15.3%) patients received any reperfusion treatment. Of these, 84.7% received I.V. fibrinolytic, 13.2% bridging therapy, and 0.9 % primary endovascular treatment. In overall, according to initial clinical deficit by NIHSS, reperfusion treatment was associated with good outcome in mild (82.8% Vs 66.1% p=0.005), moderate (55.9 % vs. 41.6% p=0.002) and severe deficits (29.4 Vs. 18.8% p=0.002). In patients with a baseline NIHSS ≥4, multivariate analysis showed that lower NIHSS (p