Loading…

Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach

Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in...

Full description

Saved in:
Bibliographic Details
Published in:Simulation (San Diego, Calif.) Calif.), 2018-02, Vol.94 (2), p.93-104
Main Authors: Kadhim, Saleem Khalefa, Nasif, Mohammad Shakir, Al-Kayiem, Hussain H, Al-Waked, Rafat
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3
cites cdi_FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3
container_end_page 104
container_issue 2
container_start_page 93
container_title Simulation (San Diego, Calif.)
container_volume 94
creator Kadhim, Saleem Khalefa
Nasif, Mohammad Shakir
Al-Kayiem, Hussain H
Al-Waked, Rafat
description Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in the BMHV. A three-dimensional computational fluid dynamic (CFD) model was developed to investigate blood hydrodynamics and shear stresses at different cardiac cycles. A user-defined function (UDF) code was developed to model the valve leaflet motion. This UDF updates the tetrahedral mesh according to the location of the valve leaflet, which enables modeling of complicated moving geometries and achieves solution convergence with ease without the need to adjust the relaxation factor values. The agreement between the experimental and numerical results indicates that the developed model could be used with confidence to simulate BMHV motion and blood flow. Furthermore, valve leaflet and valve pivot were found to be continuously exposed to shear stresses higher than 52.3 Pa which according to previous research findings may cause damage to blood platelets.
doi_str_mv 10.1177/0037549717712603
format article
fullrecord <record><control><sourceid>sage_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1177_0037549717712603</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0037549717712603</sage_id><sourcerecordid>10.1177_0037549717712603</sourcerecordid><originalsourceid>FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3</originalsourceid><addsrcrecordid>eNp1kM1KxDAUhYMoOI7uXd4XqCZNm7RLGfyDATe6LjdpMs2QNqVpR-YxfGNbx5Xg6l74vnMWh5BbRu8Yk_KeUi7zrJTzz1JB-RlZMZmxhDPOz8lqwcnCL8lVjHtKWc6kWJGvTWj7acTRhQ49WD-5Gupjh63TEaJrJ__DIFhQPoR6VsIn9EOwzhvArobYGBwgjoOJ0URwHagZofVmhNboBjun5-rFGuGA_mBAHWGKrttBG7rg3dg4DdjPpaiba3Jh0Udz83vX5OPp8X3zkmzfnl83D9tE85SPiRIFT5VluSxrKQ1XQumiwEzYurS2QGaLnAslUElkJcsKqoU1c0ArWYhU8TWhp149hBgHY6t-cC0Ox4rRapm0-jvpHElOkYg7U-3DNMybxf_9bz9-epk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach</title><source>Sage Journals Online</source><creator>Kadhim, Saleem Khalefa ; Nasif, Mohammad Shakir ; Al-Kayiem, Hussain H ; Al-Waked, Rafat</creator><creatorcontrib>Kadhim, Saleem Khalefa ; Nasif, Mohammad Shakir ; Al-Kayiem, Hussain H ; Al-Waked, Rafat</creatorcontrib><description>Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in the BMHV. A three-dimensional computational fluid dynamic (CFD) model was developed to investigate blood hydrodynamics and shear stresses at different cardiac cycles. A user-defined function (UDF) code was developed to model the valve leaflet motion. This UDF updates the tetrahedral mesh according to the location of the valve leaflet, which enables modeling of complicated moving geometries and achieves solution convergence with ease without the need to adjust the relaxation factor values. The agreement between the experimental and numerical results indicates that the developed model could be used with confidence to simulate BMHV motion and blood flow. Furthermore, valve leaflet and valve pivot were found to be continuously exposed to shear stresses higher than 52.3 Pa which according to previous research findings may cause damage to blood platelets.</description><identifier>ISSN: 0037-5497</identifier><identifier>EISSN: 1741-3133</identifier><identifier>DOI: 10.1177/0037549717712603</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Simulation (San Diego, Calif.), 2018-02, Vol.94 (2), p.93-104</ispartof><rights>The Author(s) 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3</citedby><cites>FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923,79134</link.rule.ids></links><search><creatorcontrib>Kadhim, Saleem Khalefa</creatorcontrib><creatorcontrib>Nasif, Mohammad Shakir</creatorcontrib><creatorcontrib>Al-Kayiem, Hussain H</creatorcontrib><creatorcontrib>Al-Waked, Rafat</creatorcontrib><title>Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach</title><title>Simulation (San Diego, Calif.)</title><description>Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in the BMHV. A three-dimensional computational fluid dynamic (CFD) model was developed to investigate blood hydrodynamics and shear stresses at different cardiac cycles. A user-defined function (UDF) code was developed to model the valve leaflet motion. This UDF updates the tetrahedral mesh according to the location of the valve leaflet, which enables modeling of complicated moving geometries and achieves solution convergence with ease without the need to adjust the relaxation factor values. The agreement between the experimental and numerical results indicates that the developed model could be used with confidence to simulate BMHV motion and blood flow. Furthermore, valve leaflet and valve pivot were found to be continuously exposed to shear stresses higher than 52.3 Pa which according to previous research findings may cause damage to blood platelets.</description><issn>0037-5497</issn><issn>1741-3133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kM1KxDAUhYMoOI7uXd4XqCZNm7RLGfyDATe6LjdpMs2QNqVpR-YxfGNbx5Xg6l74vnMWh5BbRu8Yk_KeUi7zrJTzz1JB-RlZMZmxhDPOz8lqwcnCL8lVjHtKWc6kWJGvTWj7acTRhQ49WD-5Gupjh63TEaJrJ__DIFhQPoR6VsIn9EOwzhvArobYGBwgjoOJ0URwHagZofVmhNboBjun5-rFGuGA_mBAHWGKrttBG7rg3dg4DdjPpaiba3Jh0Udz83vX5OPp8X3zkmzfnl83D9tE85SPiRIFT5VluSxrKQ1XQumiwEzYurS2QGaLnAslUElkJcsKqoU1c0ArWYhU8TWhp149hBgHY6t-cC0Ox4rRapm0-jvpHElOkYg7U-3DNMybxf_9bz9-epk</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Kadhim, Saleem Khalefa</creator><creator>Nasif, Mohammad Shakir</creator><creator>Al-Kayiem, Hussain H</creator><creator>Al-Waked, Rafat</creator><general>SAGE Publications</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201802</creationdate><title>Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach</title><author>Kadhim, Saleem Khalefa ; Nasif, Mohammad Shakir ; Al-Kayiem, Hussain H ; Al-Waked, Rafat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kadhim, Saleem Khalefa</creatorcontrib><creatorcontrib>Nasif, Mohammad Shakir</creatorcontrib><creatorcontrib>Al-Kayiem, Hussain H</creatorcontrib><creatorcontrib>Al-Waked, Rafat</creatorcontrib><collection>CrossRef</collection><jtitle>Simulation (San Diego, Calif.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kadhim, Saleem Khalefa</au><au>Nasif, Mohammad Shakir</au><au>Al-Kayiem, Hussain H</au><au>Al-Waked, Rafat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach</atitle><jtitle>Simulation (San Diego, Calif.)</jtitle><date>2018-02</date><risdate>2018</risdate><volume>94</volume><issue>2</issue><spage>93</spage><epage>104</epage><pages>93-104</pages><issn>0037-5497</issn><eissn>1741-3133</eissn><abstract>Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in the BMHV. A three-dimensional computational fluid dynamic (CFD) model was developed to investigate blood hydrodynamics and shear stresses at different cardiac cycles. A user-defined function (UDF) code was developed to model the valve leaflet motion. This UDF updates the tetrahedral mesh according to the location of the valve leaflet, which enables modeling of complicated moving geometries and achieves solution convergence with ease without the need to adjust the relaxation factor values. The agreement between the experimental and numerical results indicates that the developed model could be used with confidence to simulate BMHV motion and blood flow. Furthermore, valve leaflet and valve pivot were found to be continuously exposed to shear stresses higher than 52.3 Pa which according to previous research findings may cause damage to blood platelets.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><doi>10.1177/0037549717712603</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0037-5497
ispartof Simulation (San Diego, Calif.), 2018-02, Vol.94 (2), p.93-104
issn 0037-5497
1741-3133
language eng
recordid cdi_crossref_primary_10_1177_0037549717712603
source Sage Journals Online
title Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T21%3A57%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Computational%20fluid%20dynamics%20simulation%20of%20blood%20flow%20profile%20and%20shear%20stresses%20in%20bileaflet%20mechanical%20heart%20valve%20by%20using%20monolithic%20approach&rft.jtitle=Simulation%20(San%20Diego,%20Calif.)&rft.au=Kadhim,%20Saleem%20Khalefa&rft.date=2018-02&rft.volume=94&rft.issue=2&rft.spage=93&rft.epage=104&rft.pages=93-104&rft.issn=0037-5497&rft.eissn=1741-3133&rft_id=info:doi/10.1177/0037549717712603&rft_dat=%3Csage_cross%3E10.1177_0037549717712603%3C/sage_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c323t-b6832bf1579d77e3b6bc88a46fd9ff8a1f8536b6ab7a191480c6febf1cb7862b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_sage_id=10.1177_0037549717712603&rfr_iscdi=true