Mediastinal sarcoid-like reaction after colon adenocarcinoma resection

We report a rare case of mediastinal sarcoid-like reaction presenting 5 years after colon adenocarcinoma resection. The lack of clinical and biochemical features suggestive of sarcoidosis and the high 18F-fluorodeoxyglucose uptake in mediastinal adenopathy, not seen previously, led us to suspect can...

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Bibliographic Details
Published in:Asian cardiovascular & thoracic annals 2015-01, Vol.23 (1), p.82-84
Main Authors: Fiorelli, Alfonso, Accardo, Marina, Orditura, Michele, Santini, Mario
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Aged
Biopsy
Colectomy - adverse effects
Colonic Neoplasms - pathology
Colonic Neoplasms - surgery
Diagnosis, Differential
Female
Fluorodeoxyglucose F18
Humans
Mediastinal Diseases - diagnosis
Mediastinal Diseases - etiology
Positron-Emission Tomography
Predictive Value of Tests
Radiopharmaceuticals
Sarcoidosis - diagnosis
Sarcoidosis - etiology
Time Factors
Tomography, X-Ray Computed
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Summary:We report a rare case of mediastinal sarcoid-like reaction presenting 5 years after colon adenocarcinoma resection. The lack of clinical and biochemical features suggestive of sarcoidosis and the high 18F-fluorodeoxyglucose uptake in mediastinal adenopathy, not seen previously, led us to suspect cancer recurrence. Pathological diagnosis obtained with a thoracoscopic biopsy confirmed sarcoidosis. Mediastinal adenopathies need to be confirmed pathologically to avoid potential interpretative pitfalls leading to toxic overtreatment.
ISSN:0218-4923
1816-5370
DOI:10.1177/0218492313519805