Arterial lignocaine concentrations following cervical plexus blockade for carotid endarterectomy

Arterial lignocaine concentrations were measured in twenty-six patients who had carotid endarterectomy performed under deep and superficial cervical plexus blockade. A dose of 6 mg/kg of 1.5% lignocaine with 1:200,000 adrenaline was used, as well as additional supplementation by the surgeons when re...

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Published in:Anaesthesia and intensive care 1991-05, Vol.19 (2), p.197-200
Main Authors: DAWSON, A. R, DYSART, R. H, AMERENA, J. V, BRANIFF, V, DAVIS, M. J, CRONIN, K. D, MASHFORD, M. L
Format: Article
Language:English
Subjects:
Aged
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Carotid Arteries - surgery
Cervical Plexus - drug effects
Endarterectomy
Female
Humans
Lidocaine - administration & dosage
Lidocaine - blood
Local anesthesia. Pain (treatment)
Male
Medical sciences
Middle Aged
Nerve Block
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Summary:Arterial lignocaine concentrations were measured in twenty-six patients who had carotid endarterectomy performed under deep and superficial cervical plexus blockade. A dose of 6 mg/kg of 1.5% lignocaine with 1:200,000 adrenaline was used, as well as additional supplementation by the surgeons when required. Concentrations obtained produced a mean peak of 5 micrograms/ml and were similar to those previously reported from multiple bilateral intercostal blockade, which is the regional technique widely considered to produce the highest systemic levels of local anaesthetic. Apart from one peak concentration of 16.9 micrograms/ml, levels were well below the convulsion threshold. We find the technique acceptable and safe for carotid surgery and lignocaine toxicity is not identified as a problem.
ISSN:0310-057X
1448-0271
DOI:10.1177/0310057x9101900207