Choroidal features in non-neovascular and neovascular pachychoroid diseases

• Published in: European journal of ophthalmology 2024-07, Vol.34 (4), p.1191-1200
• Main Authors: Hachicha, Ines, Bouraoui, Rim, El Matri, Leila, Masmoudi, Marwa, Ben Aoun, Safa, Bouchoucha, Saker, Chebil, Ahmed, Limaiem, Rim, El Matri, Khaled
• Format: Article
• Language: English
• ISSN: 1120-6721; 1724-6016
• DOI: 10.1177/11206721231210755

Purpose To evaluate choroidal findings on multimodal imaging in eyes within pachychoroid spectrum diseases and to compare quantitative and qualitative choroidal features between non-neovascular (NNV-PDS) and neovascular (NV-PDS) pachychoroid diseases Methods Retrospective cross-sectional study comparing between NV-PDS and NNV-PDS. All patients underwent multimodal imaging including infracyanine green angiography (IFCGA) and swept source optical coherence tomography (OCT) and angiography (OCT-A). The following parameters were analyzed: subfoveal choroidal thickness (SFCT), choroidal vascular index (CVI), presence of pachyvessels and choroidal vascular interconnections (CVIC), presence of choroidal neovascularization and choriocapillaris density. Results Of the 87 eyes included in the study, 63 eyes (73%) had NNV-PDS and 24 eyes (27%) had NV-PDS. Mean SFCT and CVI were significantly higher in NNV-PDS group (p = 0.01; p = 0.022). Pachyvessels were more diffusely distributed in NNV-PD group and more focally distributed in NV-PDS group (p = 0.029). CVIC were more frequently noted in NV-PDS group (p = 0.024). A higher CVI was associated to a thicker choroid (p