Optical coherence tomography angiography analysis in patients with intracranial hypertension

Introduction Evidence on peripapillary microvasculature in intracranial hypertension (IH) after the regression of papilledema is still scarce. The aim of this preliminary study was to determine the association between structural changes in the optic nerve and the retina and peripapillary microvascul...

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Published in:European journal of ophthalmology 2024-09, Vol.34 (5), p.1586-1593
Main Authors: Remolí-Sargues, Lidia, Monferrer-Adsuara, Clara, López-Salvador, Belén, García-Villanueva, Carolina, Gracia-García, Alicia, Castro-Navarro, Verónica, Cervera-Taulet, Enrique
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Language:English
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Summary:Introduction Evidence on peripapillary microvasculature in intracranial hypertension (IH) after the regression of papilledema is still scarce. The aim of this preliminary study was to determine the association between structural changes in the optic nerve and the retina and peripapillary microvasculature in patients with IIH. Methods We conducted a retrospective study. The study included 39 eyes of 21 patients with IIH. Treatment for IIH and history of obesity were registered from each patient. Moreover, OCT analysis including retinal nerve fiber layer (RNFL) thickness and ganglion cell-inner plexiform layer (GCIPL) thickness, and OCTA analysis including perfusion density (PD) and flux index (FI) of the radial peripapillary capillary plexus were performed. Results Correlation analysis revealed a high correlation between GCIPL thickness and peripapillary PD and FI (p  0,7), whereas the degree of correlation between RNFL thickness and peripapillary microvascular parameters was low (p 
ISSN:1120-6721
1724-6016
DOI:10.1177/11206721241228349