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Rufforone: A New Styrylpyrone from Sanrafaelia ruffonammari

A new styrylpyrone, 6-(7-hydroxy-8-methoxystyryl)-4-methoxypyran-2-one (1), together with two known styrylpyrones, 6-(7,8-epoxystyryl)-4-methoxypyran-2-one (2) and 6-(7,8-dihydroxystyryl)-4-methoxypyran-2-one (3) were isolated from the stem bark of Sanrafaelia ruffonammari Verdc. 6-(7,8-Epoxystyryl)...

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Bibliographic Details
Published in:Natural product communications 2007-09, Vol.2 (9)
Main Authors: Makangara, John J., Hirai, Nobuhiro, Inomata, Masahiro, Murakami, Akira, Ohigashi, Hajime
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Request full text
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Summary:A new styrylpyrone, 6-(7-hydroxy-8-methoxystyryl)-4-methoxypyran-2-one (1), together with two known styrylpyrones, 6-(7,8-epoxystyryl)-4-methoxypyran-2-one (2) and 6-(7,8-dihydroxystyryl)-4-methoxypyran-2-one (3) were isolated from the stem bark of Sanrafaelia ruffonammari Verdc. 6-(7,8-Epoxystyryl)-4-methoxypyran-2-one exhibited high inhibitory activity to interferon-γ-induced nitric oxide generation in RAW264.7 macrophages, whereas the other two showed no activity.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X0700200906