Sigmoidine L, A New Antibacterial Flavonoid from Erythrina Sigmoidea (Fabaceae)

Chemical analyses of the stem bark of Erythrina sigmoidea (Fabaceae) yielded a new flavonoid, designated sigmoidin L (1), the known erythrinasinate, E-p-coumaric acid docosylester, and 3′-prenylnaringinin, reported here for the first time for the stem bark of E.sigmoidea. The structure of 1 was esta...

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Bibliographic Details
Published in:Natural product communications 2007-11, Vol.2 (11)
Main Authors: Kouam, Jacques, Etoa, François-Xavier, Mabeku, Laure BrigitteKouitcheu, Fomum, Zacharias Tanee
Format: Article
Language:English
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Summary:Chemical analyses of the stem bark of Erythrina sigmoidea (Fabaceae) yielded a new flavonoid, designated sigmoidin L (1), the known erythrinasinate, E-p-coumaric acid docosylester, and 3′-prenylnaringinin, reported here for the first time for the stem bark of E.sigmoidea. The structure of 1 was established by chemical and spectroscopic means as 5,7, 3′,4′-tetrahydroxy-5′-[3″-methyl-4″-oxobut-(1″Z) enyl]flavanone. Sigmoidin L exhibited significant antibacterial potency in vitro against Staphylococus aureus and Proteus vulgaris.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X0700201111