Screening Study of Potential Lead Compounds for Natural Product Based Fungicides from Juniperus Lucayana

Based on structure and detoxification data, chemical transformations of 12-hydroxywiddrol (3) isolated from the wood of Juniperus lucayana were performed leading to hemisynthetic derivatives with improved fungicidal activity against Botrytis cinerea, a pathogenic fungus affecting commercial crops.

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Bibliographic Details
Published in:Natural product communications 2008-04, Vol.3 (4)
Main Authors: Nuñez, Yarelis Ortíz, Salabarria, Iraida Spengler, Collado, Isidro G., Hernández-Galán, Rosario
Format: Article
Language:English
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Summary:Based on structure and detoxification data, chemical transformations of 12-hydroxywiddrol (3) isolated from the wood of Juniperus lucayana were performed leading to hemisynthetic derivatives with improved fungicidal activity against Botrytis cinerea, a pathogenic fungus affecting commercial crops.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X0800300401