(-)-Sclerotiorin from an Unidentified Marine Fungus as an Anti-meiotic and Antifungal Agent

(-)-Sclerotiorin, isolated and purified from the fermented broth of an unidentified marine fungus (98F134), inhibited the maturation of starfish oocytes induced by 1-methyl adenine with an IC50 value of 0.50 μM. (-)-Sclerotiorin also showed antifungal activity against Saccharomyces Cerevisiae, Asper...

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Published in:Natural product communications 2010-11, Vol.5 (11)
Main Authors: Bao, Li, Xu, Zhenyu, Niu, Shu-bin, Namikoshi, Michio, Kobayashi, Hisayoshi, Liu, Hong-wei
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Language:English
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creator Bao, Li
Xu, Zhenyu
Niu, Shu-bin
Namikoshi, Michio
Kobayashi, Hisayoshi
Liu, Hong-wei
description (-)-Sclerotiorin, isolated and purified from the fermented broth of an unidentified marine fungus (98F134), inhibited the maturation of starfish oocytes induced by 1-methyl adenine with an IC50 value of 0.50 μM. (-)-Sclerotiorin also showed antifungal activity against Saccharomyces Cerevisiae, Aspergilus Fumigatus, Alternaria Longipes, Piricularia Oryzae, Verticillium Albo-Atrum, Fusarium Culmorum, and F. nivale with IC50 values less than 20 μg/mL.
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title (-)-Sclerotiorin from an Unidentified Marine Fungus as an Anti-meiotic and Antifungal Agent
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