Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells

Enzyme-treated asparagus extract (ETAS) contains various phytochemicals. It has been reported that ETAS protected early cognitive impairment of SAMP8 mice and Aβ-induced reduction of PC12 cell viability. In addition, ETAS had several functions on healthy people. The purpose of the present study was...

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Bibliographic Details
Published in:Natural product communications 2017-10, Vol.12 (10)
Main Authors: Koda, Tomoko, Takanari, Jun, Kitadate, Kentaro, Imai, Hideki
Format: Article
Language:English
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Summary:Enzyme-treated asparagus extract (ETAS) contains various phytochemicals. It has been reported that ETAS protected early cognitive impairment of SAMP8 mice and Aβ-induced reduction of PC12 cell viability. In addition, ETAS had several functions on healthy people. The purpose of the present study was to investigate the effects of ETAS on normal memory function of rats and neurite-outgrowth of PC12 cells. ETAS significantly accelerated learning acquisition in in vivo and neurite-outgrowth in in vitro study. In conclusion, ETAS affected on memory function in early stage in normal rats. The basis of this effect may induce neurite-outgrowth in neurons.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1701201027