New Acetylated Saponins from the Leaves of Trevesia palmata

Two new acetylated saponins, acetyltrevesiasaponins A (1) and B (2), were isolated from the leaves of Trevesia palmata. Their chemical structures were determined by analysis of HR-ESI-MS and NMR spectra. Compound 2 was also confirmed by alkaline hydrolysis and identification its prosapogenin 2a. Com...

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Bibliographic Details
Published in:Natural product communications 2018-04, Vol.13 (4)
Main Authors: Thao, Le Thi Thanh, Quyen, Do, Vu, Duong Binh, Tai, Bui Huu, Van Kiem, Phan
Format: Article
Language:English
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Summary:Two new acetylated saponins, acetyltrevesiasaponins A (1) and B (2), were isolated from the leaves of Trevesia palmata. Their chemical structures were determined by analysis of HR-ESI-MS and NMR spectra. Compound 2 was also confirmed by alkaline hydrolysis and identification its prosapogenin 2a. Compounds 1, 2, and 2a were evaluated inhibitory effect on NO production in LPS stimulated BV2 cells. Compound 2 showed weak activity (IC50 40.7 μM).
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1801300407