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A New Flavone Glycoside From Lumnitzera littorea with In Vitro α-Glucosidase Inhibitory Activity

A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison...

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Bibliographic Details
Published in:Natural product communications 2019-06, Vol.14 (6)
Main Authors: Thuy, Nguyen T. L., Thuy, Pham T., Tung, Bui T., Loc, Huynh T., Dang, Truong T. T., Ngoc, Le L., Duc, Nguyen X., Dung, Le T., Hansen, Poul E., Phung, Nguyen K. P.
Format: Article
Language:English
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Summary:A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X19851361