One New Veratramine-Type Alkaloid From Veratrum maackii var. japonicum and Antioxidative Activities of Isolated Compounds

A new veratramine-type alkaloid (1), along with 4 known compounds (2-5), was isolated from the roots of Veratrum maackii var. japonicum (Baker) T. Shimizu. Their structures were elucidated on the basis of NMR and mass spectroscopic data. All compounds were evaluated for their antioxidant activities...

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Bibliographic Details
Published in:Natural product communications 2020-07, Vol.15 (7)
Main Authors: Kim, Ji-Yul, Son, Eunjung, Kim, Dong-Seon
Format: Article
Language:English
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Summary:A new veratramine-type alkaloid (1), along with 4 known compounds (2-5), was isolated from the roots of Veratrum maackii var. japonicum (Baker) T. Shimizu. Their structures were elucidated on the basis of NMR and mass spectroscopic data. All compounds were evaluated for their antioxidant activities using 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS + ) and 2,2-diphenyl-1-picrylhydrazyl (DPPH·) radical scavenging assays. Compounds 1 and 3-5 showed ABTS+ radical scavenging activity with IC50 values ranging from 15.0 to 85.7 μM.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X20939408