Investigation of False Positive and False Negative Signs in Methionine-PET

PET with L-methyl-11C-methionine (Met-PET) is a useful tool for differentiating cerebral tumor from normal brain tissue, but some observations showed a high accumulation of methionine in non-tumorous lesions. We evaluated whether Met-PET was clinically useful in distinguishing tumor from non-tumor i...

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Bibliographic Details
Published in:Rivista di neuroradiologia 1998-11, Vol.11 (2_suppl), p.87-90
Main Authors: Tsuyuguchi, N., Sunada, I., Iwai, Y., Ohata, K., Matsuoka, Y., Tanaka, K., Hakuba, A.
Format: Article
Language:English
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Summary:PET with L-methyl-11C-methionine (Met-PET) is a useful tool for differentiating cerebral tumor from normal brain tissue, but some observations showed a high accumulation of methionine in non-tumorous lesions. We evaluated whether Met-PET was clinically useful in distinguishing tumor from non-tumor in intracranial lesions. We investigated 50 cases of brain lesions. We had four non-tumorous lesions with an accumulation (false positive) and five tumorous lesions with no accumulation (false negative) in Met-PET. It should be kept in mind that there is a possibility of tumorous or non tumorous lesions in the presence of a low or high accumulation of methionine.
ISSN:1971-4009
1120-9976
2385-1996
DOI:10.1177/19714009980110S227