THE HISTOCHEMICAL DEMONSTRATION OF TRACE METALS IN LEUKOCYTES

Histochemical methods designed to demonstrate Zn++, Cu++, Co++, Mg++, Mn++, Fe++ and Fe+++ have been applied to blood smears. Metallic elements have been found only in the leukocytes belonging to the myeloid series of cells. The neutrophil was found to contain Zn++ and small amounts of Cu++; the eos...

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Bibliographic Details
Published in:The journal of histochemistry and cytochemistry 1960-03, Vol.8 (2), p.124-130
Main Author: MCNARY, WILLIAM F., JR
Format: Article
Language:English
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Summary:Histochemical methods designed to demonstrate Zn++, Cu++, Co++, Mg++, Mn++, Fe++ and Fe+++ have been applied to blood smears. Metallic elements have been found only in the leukocytes belonging to the myeloid series of cells. The neutrophil was found to contain Zn++ and small amounts of Cu++; the eosinophil, on the other hand, was found to contain large amounts of Cu++ and smaller amounts of Zn++. Basophils were not reported as they could not be identified. Mg++ and Mn++ were present in both the neutrophil and the cosinophil while Co++ was found only in the cosinophil. Iron in either the ferric or ferrous state was not demonstrated in any of the leukocytes in this investigation.
ISSN:0022-1554
1551-5044
DOI:10.1177/8.2.124