HTLV-1 HBZ: stop making sense

An antisense-encoded protein of HTLV-1 is dispensable for infection and transformation of T cells in vitro, yet modulates viral infectivity and persistence in vivo. Negative-strand–encoded retrovirus proteins may provide new targets for attenuating viral replication and pathogenesis.

Saved in:
Bibliographic Details
Published in:Blood 2006-05, Vol.107 (10), p.3813-3814
Main Author: Feuer, Gerold
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An antisense-encoded protein of HTLV-1 is dispensable for infection and transformation of T cells in vitro, yet modulates viral infectivity and persistence in vivo. Negative-strand–encoded retrovirus proteins may provide new targets for attenuating viral replication and pathogenesis.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2006-03-005199