Survival Analysis of Adults with Acute Lymphoblastic Leukemia in Ecuador

Background Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults. Unfortunately, in Ecuador there are no survival studies in patients ≥15 years with ALL, thus, this is the first national report. The aim of the study was to describe clinical-demographic characteristics...

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Bibliographic Details
Published in:Blood 2023-11, Vol.142 (Supplement 1), p.1503-1503
Main Authors: Plaza, Carlos, Sabado, Brenner, Chisesi, Teodoro, Granja, Manuel A, Orquera, Andrés, Pacheco, Maria Augusta, Quiñonez, Jairo Manuel, Trujillo, Maria Del Carmen, Navarrete, Danilo A, Sanchez, Lorena, Ramírez, Johanna, Oliveros-Alvear, Jorge
Format: Article
Language:English
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Summary:Background Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults. Unfortunately, in Ecuador there are no survival studies in patients ≥15 years with ALL, thus, this is the first national report. The aim of the study was to describe clinical-demographic characteristics and overall survival (OS). Methods Medical records of 628 patients from 8 reference hospitals in Ecuador with acute lymphoblastic leukemia (ALL) aged ≥15 years, diagnosed between January/2015 and December/2022, were retrospectively reviewed. A high-risk group was defined as: age ≥ 35 years ; ≥ 30,000/mm3 leukocytes in B-cell acute lymphoblastic leukemia (B-ALL) or ≥ 100,000/mm3 leukocytes in T-cell acute lymphoblastic leukemia (ALL- T) ; CNS infiltration at diagnosis, and/or if EMR was not reached (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2023-189237