Epidemiological Trends in Incidence, Death and Associated Risk Factors of Leukemia 1990-2021 and Projection to 2040

Introduction: Leukemia constitutes about 3.1% of all newly diagnosed cancer cases and 3.9% of deaths due to cancer in 2024 in the US. We aim to investigate the epidemiological trends (incidence and death rates) and the risk factors of Leukemia at global and regional level. Methods: The study analyze...

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Bibliographic Details
Published in:Blood 2024-11, Vol.144 (Supplement 1), p.1477-1477
Main Authors: Kundu, Rupayan, Kal, Niladri, Singh, Abhay, Mukherjee, Sudipto, Maiti, Abhishek, Ball, Somedeb, Jain, Akriti G.
Format: Article
Language:English
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Summary:Introduction: Leukemia constitutes about 3.1% of all newly diagnosed cancer cases and 3.9% of deaths due to cancer in 2024 in the US. We aim to investigate the epidemiological trends (incidence and death rates) and the risk factors of Leukemia at global and regional level. Methods: The study analyzed data from 1990 to 2021, obtained from the Global Health Data Exchange 2021 database which is a comprehensive catalog of global health and demographic data, providing access to a wide range of datasets around the world. This study described the age-standardized rates (per 100,000 patient-years) of incidence (ASIR), death (ASDR) and attributable risk factors of leukemia: overall, Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Chronic Lymphocytic Leukemia (CLL). Regions were stratified by Sociodemographic Index (SDI) ranged from 0 (minimal development) to 1 (maximal development) and was classified as high (>0.715), high-middle (0.625 to .0715), middle (0.558 to 0.624), low-middle (0.378 to .0557), and low (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2024-211457