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Anaphylaxis Associated with Administration of Repeated Courses of Rasburicase: A Research On Adverse Drug Events and Reports (RADAR) Project

Abstract 1351 Rasburicase (recombinant urate oxidase) is used to rapidly metabolize uric acid in patients with hyperuricemia. Rasburicase is considered immunogenic given that it is produced by a genetically modified Saccharomyces cerevisiae. Rasburicase labeling indicates that anaphylaxis rarely occ...

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Bibliographic Details
Published in:Blood 2012-11, Vol.120 (21), p.1351-1351
Main Authors: Allen, Katherine C, Champlain, Amanda H, Cotliar, Jonathan, Belknap, Steven M., West, Dennis P., Mehta, Jayesh, Trifilio, Steven
Format: Article
Language:English
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Summary:Abstract 1351 Rasburicase (recombinant urate oxidase) is used to rapidly metabolize uric acid in patients with hyperuricemia. Rasburicase is considered immunogenic given that it is produced by a genetically modified Saccharomyces cerevisiae. Rasburicase labeling indicates that anaphylaxis rarely occurs (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V120.21.1351.1351