IRREVERSIBLE TOXIC "INCLUSION BODY" ANEMIA

1. "Inclusion bodies," distinguishable from the Howell-Jolly bodies, were observed in the red blood cells of a patient with a severe refractory fatal anemia, who had been receiving erythrol tetranitrate over a period of one year. 2. "Bodies" with similar staining characteristics...

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Bibliographic Details
Published in:Blood 1948-04, Vol.3 (4), p.349-360
Main Authors: FERTMAN, M. H., DOAN, CHARLES A.
Format: Article
Language:English
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Summary:1. "Inclusion bodies," distinguishable from the Howell-Jolly bodies, were observed in the red blood cells of a patient with a severe refractory fatal anemia, who had been receiving erythrol tetranitrate over a period of one year. 2. "Bodies" with similar staining characteristics were reproduced in cats with large oral doses of erythrol tetranitrate and other nitrates. These were generally accompanied by a temporary fall in the red cell count, followed by recovery upon withdrawal of the drug.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V3.4.349.349