Strategies to improve tolerability of rivastigmine: a case series

ABSTRACT Cholinesterase inhibitors, which act by inhibiting the degradation of acetylcholine in the brain, form the mainstay of therapy for AD. Predominant adverse events are cholinergic in nature, the most frequent being gastrointestinal side effects. Here we present a case series of patients with...

Full description

Saved in:
Bibliographic Details
Published in:Current medical research and opinion 2007-01, Vol.23 (1), p.93-95
Main Authors: Venkatesh, K., Bullock, R., Akbas¸, A.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - drug therapy
Cholinesterase inhibitor
Cholinesterase Inhibitors - adverse effects
Dementia
Female
Gastrointestinal Diseases - etiology
Gastrointestinal Diseases - prevention & control
Humans
Male
Middle Aged
Phenylcarbamates - adverse effects
Rivastigmine
Titration
Tolerability
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT Cholinesterase inhibitors, which act by inhibiting the degradation of acetylcholine in the brain, form the mainstay of therapy for AD. Predominant adverse events are cholinergic in nature, the most frequent being gastrointestinal side effects. Here we present a case series of patients with dementia who were treated with non-standard titration regimens of oral rivastigmine in order to achieve improved tolerability.
ISSN:0300-7995
1473-4877
DOI:10.1185/030079906X162791