Preoperative Calcitonin Levels Are Predictive of Tumor Size and Postoperative Calcitonin Normalization in Medullary Thyroid Carcinoma

Medullary thyroid carcinoma (MTC) is a calcitonin (CT)-secreting endocrine tumor. Although plasma CT level is a specific and sensitive marker of MTC, its preoperative usefulness in predicting tumor size and postoperative CT normalization has not been documented. From a nationwide database set up by...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2000-02, Vol.85 (2), p.919-919
Main Authors: Cohen, Régis, Campos, José-Marie, Salaün, Carole, Massoud Heshmati, Hassan, Kraimps, Jean-Louis, Proye, Charles, Sarfati, Émile, Henry, Jean-François, Niccoli-Sire, Patricia, Modigliani, Elisabeth
Format: Article
Language:English
Subjects:
Biological and medical sciences
Endocrinopathies
Malignant tumors
Medical sciences
Thyroid. Thyroid axis (diseases)
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Summary:Medullary thyroid carcinoma (MTC) is a calcitonin (CT)-secreting endocrine tumor. Although plasma CT level is a specific and sensitive marker of MTC, its preoperative usefulness in predicting tumor size and postoperative CT normalization has not been documented. From a nationwide database set up by the French CT Tumor Study Group, 226 MTC patients were selected according to the following criteria: preoperative CT level determination by an immunoradiometric assay (normal value,
ISSN:0021-972X
1945-7197
DOI:10.1210/jcem.85.2.6556