Synthesis, Antitumour and Anti-HIV Screening of Oxazolidines and Oxazolidinones Derivatives

Some N‐phenyl(thio)carbamoyl‐2‐iminooxazolidines and 2‐oxazolidinones were synthesized via 2‐amino‐2‐oxazolines and tested as antiviral and antitumour agents. Moderate antitumour activity was found for the 5‐(1‐phenyl‐4‐piperazinyl)methyl substituted compounds.

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Bibliographic Details
Published in:Pharmacy and Pharmacology Communications 1999-03, Vol.5 (3), p.211-215
Main Authors: CHAIMBAULT, C., BOSC, J. J., JARRY, C.
Format: Article
Language:English
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Summary:Some N‐phenyl(thio)carbamoyl‐2‐iminooxazolidines and 2‐oxazolidinones were synthesized via 2‐amino‐2‐oxazolines and tested as antiviral and antitumour agents. Moderate antitumour activity was found for the 5‐(1‐phenyl‐4‐piperazinyl)methyl substituted compounds.
ISSN:1460-8081
2042-7158
DOI:10.1211/146080899128734622