Systolic Dysfunction in Urban Japan: Niigata-Sado Heart Failure Study

Background Heart failure (HF), which can be caused by left ventricular systolic dysfunction (LVSD), is a growing problem in developed countries with a large aging population. The aim of the present study was to characterize outpatients with LVSD in the adult population (45-84 years) in an urban Japa...

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Published in:Circulation Journal 2008, Vol.72(3), pp.349-357
Main Authors: Ramadan, Mahmoud M., Ohno, Yukiko, Okura, Yuji, Tanabe, Naohito, Suzuki, Keisuke, Abe, Akira, Tamura, Makoto, Hatano, Tatsuro, Matsubara, Taku, Tamura, Yusuke, Yokoyama, Akihiro, Yamamoto, Tomohiko, Otsuka, Hideaki, Okada, Yoshinobu, Oda, Hirotaka, Yamamoto, Yasuyuki, Tsuda, Takashi, Ohno, Michiko, Yamazoe, Masaru, Shimotori, Takashi, Arai, Hiroyuki, Kodama, Makoto, Aizawa, Yoshifusa
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Language:English
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Echocardiography
Heart failure
Niigata-Sado Heart Failure Study
Systolic dysfunction
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container_end_page 357
container_issue 3
container_start_page 349
container_title Circulation Journal
container_volume 72
creator Ramadan, Mahmoud M.
Ohno, Yukiko
Okura, Yuji
Tanabe, Naohito
Suzuki, Keisuke
Abe, Akira
Tamura, Makoto
Hatano, Tatsuro
Matsubara, Taku
Tamura, Yusuke
Yokoyama, Akihiro
Yamamoto, Tomohiko
Otsuka, Hideaki
Okada, Yoshinobu
Oda, Hirotaka
Yamamoto, Yasuyuki
Tsuda, Takashi
Ohno, Michiko
Yamazoe, Masaru
Shimotori, Takashi
Arai, Hiroyuki
Kodama, Makoto
Aizawa, Yoshifusa
description Background Heart failure (HF), which can be caused by left ventricular systolic dysfunction (LVSD), is a growing problem in developed countries with a large aging population. The aim of the present study was to characterize outpatients with LVSD in the adult population (45-84 years) in an urban Japanese community (Niigata City), and delineate their characteristics in comparison with those in a rural one (Sado). Methods and Results Over a 5-year period, 1,297 patients (67% males) with LVSD (defined as ejection fraction ≤50%) were extracted from 87,953 echocardiography records available in 15 hospitals in Niigata City. The proportion of LVSD increased progressively with age (p-for-trend
doi_str_mv 10.1253/circj.72.349
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The aim of the present study was to characterize outpatients with LVSD in the adult population (45-84 years) in an urban Japanese community (Niigata City), and delineate their characteristics in comparison with those in a rural one (Sado). Methods and Results Over a 5-year period, 1,297 patients (67% males) with LVSD (defined as ejection fraction ≤50%) were extracted from 87,953 echocardiography records available in 15 hospitals in Niigata City. The proportion of LVSD increased progressively with age (p-for-trend &lt;0.0001), reaching 1-2% in those aged ≥75 years. The prevalence of comorbidities was noticeable (47% had hypertension, 41% myocardial ischemia, 34% atrial fibrillation, 33% previous hospitalization because of congestive HF, 27% cerebral stroke). In comparison with Sado, Niigata patients were younger, with a higher prevalence of comorbidities (hypertension, diabetes, dyslipidemia, and cerebral stroke). Conclusions As the proportion of LVSD cases increases progressively with age, it is expected to simulate a future epidemic. The differences between patients' characteristics and disease patterns in urban and rural communities may favor individually tailoring preventive strategies for HF in these areas. (Circ J 2008; 72: 349 - 357)</description><identifier>ISSN: 1346-9843</identifier><identifier>EISSN: 1347-4820</identifier><identifier>DOI: 10.1253/circj.72.349</identifier><language>eng</language><publisher>The Japanese Circulation Society</publisher><subject>Echocardiography ; Heart failure ; Niigata-Sado Heart Failure Study ; Systolic dysfunction</subject><ispartof>Circulation Journal, 2008, Vol.72(3), pp.349-357</ispartof><rights>2008 THE JAPANESE CIRCULATION SOCIETY</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c378t-7f00d1e5bbd16d912d7f7674946da964f98b1f12668a4492cc1a9eef101b1c1b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Ramadan, Mahmoud M.</creatorcontrib><creatorcontrib>Ohno, Yukiko</creatorcontrib><creatorcontrib>Okura, Yuji</creatorcontrib><creatorcontrib>Tanabe, Naohito</creatorcontrib><creatorcontrib>Suzuki, Keisuke</creatorcontrib><creatorcontrib>Abe, Akira</creatorcontrib><creatorcontrib>Tamura, Makoto</creatorcontrib><creatorcontrib>Hatano, Tatsuro</creatorcontrib><creatorcontrib>Matsubara, Taku</creatorcontrib><creatorcontrib>Tamura, Yusuke</creatorcontrib><creatorcontrib>Yokoyama, Akihiro</creatorcontrib><creatorcontrib>Yamamoto, Tomohiko</creatorcontrib><creatorcontrib>Otsuka, Hideaki</creatorcontrib><creatorcontrib>Okada, Yoshinobu</creatorcontrib><creatorcontrib>Oda, Hirotaka</creatorcontrib><creatorcontrib>Yamamoto, Yasuyuki</creatorcontrib><creatorcontrib>Tsuda, Takashi</creatorcontrib><creatorcontrib>Ohno, Michiko</creatorcontrib><creatorcontrib>Yamazoe, Masaru</creatorcontrib><creatorcontrib>Shimotori, Takashi</creatorcontrib><creatorcontrib>Arai, Hiroyuki</creatorcontrib><creatorcontrib>Kodama, Makoto</creatorcontrib><creatorcontrib>Aizawa, Yoshifusa</creatorcontrib><title>Systolic Dysfunction in Urban Japan: Niigata-Sado Heart Failure Study</title><title>Circulation Journal</title><description>Background Heart failure (HF), which can be caused by left ventricular systolic dysfunction (LVSD), is a growing problem in developed countries with a large aging population. The aim of the present study was to characterize outpatients with LVSD in the adult population (45-84 years) in an urban Japanese community (Niigata City), and delineate their characteristics in comparison with those in a rural one (Sado). Methods and Results Over a 5-year period, 1,297 patients (67% males) with LVSD (defined as ejection fraction ≤50%) were extracted from 87,953 echocardiography records available in 15 hospitals in Niigata City. The proportion of LVSD increased progressively with age (p-for-trend &lt;0.0001), reaching 1-2% in those aged ≥75 years. The prevalence of comorbidities was noticeable (47% had hypertension, 41% myocardial ischemia, 34% atrial fibrillation, 33% previous hospitalization because of congestive HF, 27% cerebral stroke). In comparison with Sado, Niigata patients were younger, with a higher prevalence of comorbidities (hypertension, diabetes, dyslipidemia, and cerebral stroke). Conclusions As the proportion of LVSD cases increases progressively with age, it is expected to simulate a future epidemic. The differences between patients' characteristics and disease patterns in urban and rural communities may favor individually tailoring preventive strategies for HF in these areas. 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The aim of the present study was to characterize outpatients with LVSD in the adult population (45-84 years) in an urban Japanese community (Niigata City), and delineate their characteristics in comparison with those in a rural one (Sado). Methods and Results Over a 5-year period, 1,297 patients (67% males) with LVSD (defined as ejection fraction ≤50%) were extracted from 87,953 echocardiography records available in 15 hospitals in Niigata City. The proportion of LVSD increased progressively with age (p-for-trend &lt;0.0001), reaching 1-2% in those aged ≥75 years. The prevalence of comorbidities was noticeable (47% had hypertension, 41% myocardial ischemia, 34% atrial fibrillation, 33% previous hospitalization because of congestive HF, 27% cerebral stroke). In comparison with Sado, Niigata patients were younger, with a higher prevalence of comorbidities (hypertension, diabetes, dyslipidemia, and cerebral stroke). Conclusions As the proportion of LVSD cases increases progressively with age, it is expected to simulate a future epidemic. The differences between patients' characteristics and disease patterns in urban and rural communities may favor individually tailoring preventive strategies for HF in these areas. (Circ J 2008; 72: 349 - 357)</abstract><pub>The Japanese Circulation Society</pub><doi>10.1253/circj.72.349</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Echocardiography
Heart failure
Niigata-Sado Heart Failure Study
Systolic dysfunction
title Systolic Dysfunction in Urban Japan: Niigata-Sado Heart Failure Study
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