Proposed Two-molecule Intercalation between Neighboring Base Pairs of DNA

DNA intercalation of 9-aminoacridine and its derivatives was evaluated by the UV -VIS absorption-Scatchard plot technique, and it was suggested that two molecules of 9-amino-2,7-dibromoacridine were located between neighboring base pairs of DNA.

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Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1995, Vol.59 (5), p.960-961
Main Authors: Tomosaka, Hideyuki, Anzai, Kentaro, Omata, Saburo
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antineoplastic agents
Antiparasitic agents
Biological and medical sciences
General aspects
Medical sciences
Pharmacology. Drug treatments
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container_end_page 961
container_issue 5
container_start_page 960
container_title Bioscience, biotechnology, and biochemistry
container_volume 59
creator Tomosaka, Hideyuki
Anzai, Kentaro
Omata, Saburo
description DNA intercalation of 9-aminoacridine and its derivatives was evaluated by the UV -VIS absorption-Scatchard plot technique, and it was suggested that two molecules of 9-amino-2,7-dibromoacridine were located between neighboring base pairs of DNA.
doi_str_mv 10.1271/bbb.59.960
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ispartof Bioscience, biotechnology, and biochemistry, 1995, Vol.59 (5), p.960-961
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source EZB Electronic Journals Library
subjects Antibiotics. Antiinfectious agents. Antiparasitic agents
Antineoplastic agents
Antiparasitic agents
Biological and medical sciences
General aspects
Medical sciences
Pharmacology. Drug treatments
title Proposed Two-molecule Intercalation between Neighboring Base Pairs of DNA
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