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Synthesis of the L-Enantiomer of 4'-C-Ethynyl-2'-deoxycytidine

The L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine (2) was synthesized, but did not show any activity against HIV-1 up to 100 μM.

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2001-08, Vol.65 (8), p.1879-1882
Main Authors: KOHGO, Satoru, MITSUYA, Hiroaki, OHRUI, Hiroshi
Format: Article
Language:English
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Description
Summary:The L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine (2) was synthesized, but did not show any activity against HIV-1 up to 100 μM.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.65.1879