Effects of the marine unicellular alga Nannochloropsis sp. to reduce the plasma and liver cholesterol levels in male rats fed on diets with cholesterol

The effects of Nannochloropsis were studied on rats consuming hypercholesterolemic diets. The whole bio-mass and the hexane/ethanol extract increased the plasma and hepatic eicosapentaenoic and docosahexaenoic acids levels, and reduced the cholesterol levels. We also observed a higher level of propi...

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Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2003-10, Vol.67 (10), p.2266-2268
Main Authors: Werman, M.J. (Technion-Israel Inst. of Technology, Haifa), Sukenik, A, Mokady, S
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
BLOOD PLASMA
CHOLESTEROL
Cholesterol - administration & dosage
Cholesterol - analysis
Cholesterol - blood
DIET
Dietary Supplements
DOCOSAHEXAENOIC ACID
Docosahexaenoic Acids - analysis
Docosahexaenoic Acids - blood
EICOSAPENTAENOIC ACID
Eicosapentaenoic Acid - analysis
Eicosapentaenoic Acid - blood
Eukaryota
Fundamental and applied biological sciences. Psychology
Hypercholesterolemia - therapy
LIVER
Liver - chemistry
Male
Nannochloropsis
Nannochloropsis sp
plasma
rat
RATS
SEAWEEDS
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Summary:The effects of Nannochloropsis were studied on rats consuming hypercholesterolemic diets. The whole bio-mass and the hexane/ethanol extract increased the plasma and hepatic eicosapentaenoic and docosahexaenoic acids levels, and reduced the cholesterol levels. We also observed a higher level of propionate, and a lower ratio between acetate and propionate. These data suggest the efficacy of Nannochloropsis in reducing cholesterol levels.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.67.2266