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Generalized granuloma annulare in an infant clinically manifested as papules and atrophic macules: A case report

Granuloma annulare (GA) has diverse clinical manifestations including papules, plaques, and nodules on the extremities that are skin-colored, pink, or purple. Approximately 15% of all GA cases are considered generalized GA. Herein, we describe the case of a pediatric patient who initially presented...

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Bibliographic Details
Published in:World journal of clinical cases 2023-11, Vol.11 (33), p.8084-8088
Main Authors: Zhang, Dong-Yuan, Zhang, Li, Yang, Qin-Yan, Li, Jiazheng, Jiang, Hong-Chao, Xie, Yu-Cheng, Shu, Hong
Format: Article
Language:English
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Summary:Granuloma annulare (GA) has diverse clinical manifestations including papules, plaques, and nodules on the extremities that are skin-colored, pink, or purple. Approximately 15% of all GA cases are considered generalized GA. Herein, we describe the case of a pediatric patient who initially presented with papules and later developed generalized atrophic macules. Upon examination, two different morphologic lesions were histopathologically confirmed: Epithelioid nodular GA and scattered histiocytic infiltrative GA. This patient exhibited rare clinical manifestations that differed throughout the course of the disease. The varying histopathological types and clinical manifestations of GA may be linked to the different stages of the disease. This rare case demonstrates the different histopathological features of different stages and clinical manifestations of granuloma annulare in an infant.
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v11.i33.8084