Acute Sensorineural Hearing Loss: Furosemide Ototoxicity Revisited

Background Acquired sensorineural hearing loss occurs as a consequence of damage to the inner ear and may result from tumors, medications, or noise-induced acoustic trauma. Furosemide ototoxicity—manifested by tinnitus, vertigo, or hearing loss—is frequently reversible, but some cases may result in...

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Bibliographic Details
Published in:Hospital pharmacy (Philadelphia) 2008-12, Vol.43 (12), p.982-988
Main Authors: Baldwin, Kathleen A., Budzinski, Cynthia E., Shapiro, Craig J.
Format: Article
Language:English
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Summary:Background Acquired sensorineural hearing loss occurs as a consequence of damage to the inner ear and may result from tumors, medications, or noise-induced acoustic trauma. Furosemide ototoxicity—manifested by tinnitus, vertigo, or hearing loss—is frequently reversible, but some cases may result in permanent hearing loss. Purpose Because of the serious nature of this adverse drug reaction, the intent of this article is heightening the awareness of furosemide-induced ototoxicity through case presentation. Methods An updated review of the literature is provided. Results and Conclusion The case demonstrates multiple risk factors that can be used to empower readers for identification of patients who are also at high risk. Strategies are presented for avoiding further cases.
ISSN:0018-5787
1945-1253
DOI:10.1310/hpj4312-982