Isolation and Characterization of Bioactive Anti-inflammatory Flavonoids from Arisaema tortuosum Tubers

Present study was focused on the isolation and characterization of the anti-inflammatory compound(s) from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR, 1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and fraction 5 (P...

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Bibliographic Details
Published in:Asian journal of chemistry 2020-12, Vol.32 (12), p.3093-3096
Main Authors: Chakraborty, Priyanka, Mazumder, Kamalika, Bala, Nripendra Nath, Das, Sudipta
Format: Article
Language:English
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Summary:Present study was focused on the isolation and characterization of the anti-inflammatory compound(s) from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR, 1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg BW. The results indicate that PC-2 and PC-1 methanolic extract of A. tortuosum tuber may be competing for the tent in the therapy of inflammatory ailments.
ISSN:0970-7077
0975-427X
DOI:10.14233/ajchem.2020.22895