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Isolation and Characterization of Bioactive Anti-inflammatory Flavonoids from Arisaema tortuosum Tubers
Present study was focused on the isolation and characterization of the anti-inflammatory compound(s) from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR, 1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and fraction 5 (P...
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Published in: | Asian journal of chemistry 2020-12, Vol.32 (12), p.3093-3096 |
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container_end_page | 3096 |
container_issue | 12 |
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container_title | Asian journal of chemistry |
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creator | Chakraborty, Priyanka Mazumder, Kamalika Bala, Nripendra Nath Das, Sudipta |
description | Present study was focused on the isolation and characterization of the anti-inflammatory compound(s)
from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR,
1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and
fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the
isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg
BW. The results indicate that PC-2 and PC-1 methanolic extract of A. tortuosum tuber may be competing
for the tent in the therapy of inflammatory ailments. |
doi_str_mv | 10.14233/ajchem.2020.22895 |
format | article |
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1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and
fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the
isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg
BW. The results indicate that PC-2 and PC-1 methanolic extract of A. tortuosum tuber may be competing
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from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR,
1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and
fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the
isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg
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from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR,
1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and
fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the
isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg
BW. The results indicate that PC-2 and PC-1 methanolic extract of A. tortuosum tuber may be competing
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source | Alma/SFX Local Collection |
title | Isolation and Characterization of Bioactive Anti-inflammatory Flavonoids from Arisaema tortuosum Tubers |
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