Lithium toxicity in a newborn

The use of lithium salts in the treatment of affective neurosis has recently become popular. There have been no reports of neonatal lithium toxicity although it is embryopathic in other species. A newborn whose mother received lithium during the last month of pregnancy is presented. The infant manif...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1971-01, Vol.47 (1), p.94-96
Main Authors: Woody, J N, London, W L, Wilbanks, Jr, G D
Format: Article
Language:English
Subjects:
Adult
Affective Symptoms - drug therapy
Central Nervous System Diseases - chemically induced
Coma - chemically induced
Cyanosis - chemically induced
Female
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases - chemically induced
Lithium - metabolism
Lithium - poisoning
Maternal-Fetal Exchange
Muscle Cramp - chemically induced
Muscle Tonus
Pregnancy
Pregnancy Complications - drug therapy
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Description
Summary:The use of lithium salts in the treatment of affective neurosis has recently become popular. There have been no reports of neonatal lithium toxicity although it is embryopathic in other species. A newborn whose mother received lithium during the last month of pregnancy is presented. The infant manifested a 10-day course of cyanosis and lethargy with serum lithium levels in the adult toxic range. It is suggested lithium be used with caution during pregnancy.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.47.1.94