New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research

PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to diss...

Full description

Saved in:
Bibliographic Details
Published in:Acta cirúrgica brasileira 2009-04, Vol.24 (2), p.82-86
Main Authors: Lopes, Jackson Brandão, Dallan, Luís Alberto Oliveira, Moreira, Luiz Felipe Pinho, Carreiro, Mário Castro, Rodrigues, Flávia Luana Barbosa, Mendes, Pedro de Castro, Stolf, Noedir Antônio Groppo
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3
cites cdi_FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3
container_end_page 86
container_issue 2
container_start_page 82
container_title Acta cirúrgica brasileira
container_volume 24
creator Lopes, Jackson Brandão
Dallan, Luís Alberto Oliveira
Moreira, Luiz Felipe Pinho
Carreiro, Mário Castro
Rodrigues, Flávia Luana Barbosa
Mendes, Pedro de Castro
Stolf, Noedir Antônio Groppo
description PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p
doi_str_mv 10.1590/S0102-86502009000200002
format article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1590_S0102_86502009000200002</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1590_S0102_86502009000200002</sourcerecordid><originalsourceid>FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3</originalsourceid><addsrcrecordid>eNplkFFLwzAUhYMoOKe_wfyB6k3aZYlvMtQJQx_U53Kb3rBI19Yknfrv7ZyI4Ms9B-53L4fD2LmACzEzcPkEAmSm1QwkgAHYyTgO2OR3cfjHH7OTGF8BRKFEPmH9A73ztwHb5BMmvyW-xeCxaijy1PENYRwC8b6Lqesp7JHReIuh9thwrNcUfdfGKz5EckMznnVN5L7l9LEDN9SmkQsUCYNdn7Ijh02ksx-dspfbm-fFMls93t0vrleZLfIiZTON8zGgkXqujKOKak22MpIQnHS500Ipk4NB1KaShdMSCmuFVAoqQbLOp2y-_2tDF2MgV_ZjFgyfpYByV1z5XVz5r7j8C7hgY-0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research</title><source>SciELO</source><creator>Lopes, Jackson Brandão ; Dallan, Luís Alberto Oliveira ; Moreira, Luiz Felipe Pinho ; Carreiro, Mário Castro ; Rodrigues, Flávia Luana Barbosa ; Mendes, Pedro de Castro ; Stolf, Noedir Antônio Groppo</creator><creatorcontrib>Lopes, Jackson Brandão ; Dallan, Luís Alberto Oliveira ; Moreira, Luiz Felipe Pinho ; Carreiro, Mário Castro ; Rodrigues, Flávia Luana Barbosa ; Mendes, Pedro de Castro ; Stolf, Noedir Antônio Groppo</creatorcontrib><description>PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p&lt;0.01, respectively). Through a non-linear regression, an exponential relation of SS with ShpD (R²=0.915) and SS with Δt (R²= 0.917) was found. CONCLUSION: The time spent to dissect the adhesions (Δt) and the amount of sharp dissection (ShpD) are new powerful measurement tools in evaluating outcomes of the methods used to prevent pericardial adhesions. OBJETIVO: A fim de melhorar a metodologia de mensuração das aderências pericárdicas, avaliamos, durante um estudo de prevenção de aderências pericárdicas, a possibilidade da utilização de três de novas variáveis contínuas e numéricas. MÉTODOS: Para validar estas novas variáveis numéricas - tempo de dissecção (Δt), quantidade de dissecção cruenta (ShpD) e a área de colágeno na aderência (ACA) como instrumentos precisos na quantificação das aderências pericárdicas, foram analisados os dados de um estudo para prevenção de aderências que envolveu 24 porcos. Foram aplicados modelos de regressão e o teste de Spearman para avaliar a força e os tipos correlações entre os resultados do escore padrão de classificação de aderências (SS) e o Δt, entre o SS e o ShpD, e, também, entre o SS e a ACA. RESULTADOS: Foram evidenciadas correlações, estatisticamente significativas, entre o SS e o Δt, entre o SS e o ShpD, também como entre o SS e a ACA avaliadas através do teste de Spearman (r=0,897, r=0,932 , r=0,66; p&lt;0,001, respectivamente). Identificou-se, através de regreção não-linear, uma relação exponencial do SS com o ShpD (R²=0,915) e com o Δt (R²= 0,917). CONCLUSÃO: Este estudo mostrou que o Δt e o ShpD são variáveis poderosas para avaliar os resultados dos métodos utilizados para prevenção das aderências pericárdicas.</description><identifier>ISSN: 0102-8650</identifier><identifier>EISSN: 0102-8650</identifier><identifier>DOI: 10.1590/S0102-86502009000200002</identifier><language>eng</language><ispartof>Acta cirúrgica brasileira, 2009-04, Vol.24 (2), p.82-86</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3</citedby><cites>FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Lopes, Jackson Brandão</creatorcontrib><creatorcontrib>Dallan, Luís Alberto Oliveira</creatorcontrib><creatorcontrib>Moreira, Luiz Felipe Pinho</creatorcontrib><creatorcontrib>Carreiro, Mário Castro</creatorcontrib><creatorcontrib>Rodrigues, Flávia Luana Barbosa</creatorcontrib><creatorcontrib>Mendes, Pedro de Castro</creatorcontrib><creatorcontrib>Stolf, Noedir Antônio Groppo</creatorcontrib><title>New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research</title><title>Acta cirúrgica brasileira</title><description>PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p&lt;0.01, respectively). Through a non-linear regression, an exponential relation of SS with ShpD (R²=0.915) and SS with Δt (R²= 0.917) was found. CONCLUSION: The time spent to dissect the adhesions (Δt) and the amount of sharp dissection (ShpD) are new powerful measurement tools in evaluating outcomes of the methods used to prevent pericardial adhesions. OBJETIVO: A fim de melhorar a metodologia de mensuração das aderências pericárdicas, avaliamos, durante um estudo de prevenção de aderências pericárdicas, a possibilidade da utilização de três de novas variáveis contínuas e numéricas. MÉTODOS: Para validar estas novas variáveis numéricas - tempo de dissecção (Δt), quantidade de dissecção cruenta (ShpD) e a área de colágeno na aderência (ACA) como instrumentos precisos na quantificação das aderências pericárdicas, foram analisados os dados de um estudo para prevenção de aderências que envolveu 24 porcos. Foram aplicados modelos de regressão e o teste de Spearman para avaliar a força e os tipos correlações entre os resultados do escore padrão de classificação de aderências (SS) e o Δt, entre o SS e o ShpD, e, também, entre o SS e a ACA. RESULTADOS: Foram evidenciadas correlações, estatisticamente significativas, entre o SS e o Δt, entre o SS e o ShpD, também como entre o SS e a ACA avaliadas através do teste de Spearman (r=0,897, r=0,932 , r=0,66; p&lt;0,001, respectivamente). Identificou-se, através de regreção não-linear, uma relação exponencial do SS com o ShpD (R²=0,915) e com o Δt (R²= 0,917). CONCLUSÃO: Este estudo mostrou que o Δt e o ShpD são variáveis poderosas para avaliar os resultados dos métodos utilizados para prevenção das aderências pericárdicas.</description><issn>0102-8650</issn><issn>0102-8650</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNplkFFLwzAUhYMoOKe_wfyB6k3aZYlvMtQJQx_U53Kb3rBI19Yknfrv7ZyI4Ms9B-53L4fD2LmACzEzcPkEAmSm1QwkgAHYyTgO2OR3cfjHH7OTGF8BRKFEPmH9A73ztwHb5BMmvyW-xeCxaijy1PENYRwC8b6Lqesp7JHReIuh9thwrNcUfdfGKz5EckMznnVN5L7l9LEDN9SmkQsUCYNdn7Ijh02ksx-dspfbm-fFMls93t0vrleZLfIiZTON8zGgkXqujKOKak22MpIQnHS500Ipk4NB1KaShdMSCmuFVAoqQbLOp2y-_2tDF2MgV_ZjFgyfpYByV1z5XVz5r7j8C7hgY-0</recordid><startdate>20090401</startdate><enddate>20090401</enddate><creator>Lopes, Jackson Brandão</creator><creator>Dallan, Luís Alberto Oliveira</creator><creator>Moreira, Luiz Felipe Pinho</creator><creator>Carreiro, Mário Castro</creator><creator>Rodrigues, Flávia Luana Barbosa</creator><creator>Mendes, Pedro de Castro</creator><creator>Stolf, Noedir Antônio Groppo</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20090401</creationdate><title>New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research</title><author>Lopes, Jackson Brandão ; Dallan, Luís Alberto Oliveira ; Moreira, Luiz Felipe Pinho ; Carreiro, Mário Castro ; Rodrigues, Flávia Luana Barbosa ; Mendes, Pedro de Castro ; Stolf, Noedir Antônio Groppo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lopes, Jackson Brandão</creatorcontrib><creatorcontrib>Dallan, Luís Alberto Oliveira</creatorcontrib><creatorcontrib>Moreira, Luiz Felipe Pinho</creatorcontrib><creatorcontrib>Carreiro, Mário Castro</creatorcontrib><creatorcontrib>Rodrigues, Flávia Luana Barbosa</creatorcontrib><creatorcontrib>Mendes, Pedro de Castro</creatorcontrib><creatorcontrib>Stolf, Noedir Antônio Groppo</creatorcontrib><collection>CrossRef</collection><jtitle>Acta cirúrgica brasileira</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lopes, Jackson Brandão</au><au>Dallan, Luís Alberto Oliveira</au><au>Moreira, Luiz Felipe Pinho</au><au>Carreiro, Mário Castro</au><au>Rodrigues, Flávia Luana Barbosa</au><au>Mendes, Pedro de Castro</au><au>Stolf, Noedir Antônio Groppo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research</atitle><jtitle>Acta cirúrgica brasileira</jtitle><date>2009-04-01</date><risdate>2009</risdate><volume>24</volume><issue>2</issue><spage>82</spage><epage>86</epage><pages>82-86</pages><issn>0102-8650</issn><eissn>0102-8650</eissn><abstract>PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p&lt;0.01, respectively). Through a non-linear regression, an exponential relation of SS with ShpD (R²=0.915) and SS with Δt (R²= 0.917) was found. CONCLUSION: The time spent to dissect the adhesions (Δt) and the amount of sharp dissection (ShpD) are new powerful measurement tools in evaluating outcomes of the methods used to prevent pericardial adhesions. OBJETIVO: A fim de melhorar a metodologia de mensuração das aderências pericárdicas, avaliamos, durante um estudo de prevenção de aderências pericárdicas, a possibilidade da utilização de três de novas variáveis contínuas e numéricas. MÉTODOS: Para validar estas novas variáveis numéricas - tempo de dissecção (Δt), quantidade de dissecção cruenta (ShpD) e a área de colágeno na aderência (ACA) como instrumentos precisos na quantificação das aderências pericárdicas, foram analisados os dados de um estudo para prevenção de aderências que envolveu 24 porcos. Foram aplicados modelos de regressão e o teste de Spearman para avaliar a força e os tipos correlações entre os resultados do escore padrão de classificação de aderências (SS) e o Δt, entre o SS e o ShpD, e, também, entre o SS e a ACA. RESULTADOS: Foram evidenciadas correlações, estatisticamente significativas, entre o SS e o Δt, entre o SS e o ShpD, também como entre o SS e a ACA avaliadas através do teste de Spearman (r=0,897, r=0,932 , r=0,66; p&lt;0,001, respectivamente). Identificou-se, através de regreção não-linear, uma relação exponencial do SS com o ShpD (R²=0,915) e com o Δt (R²= 0,917). CONCLUSÃO: Este estudo mostrou que o Δt e o ShpD são variáveis poderosas para avaliar os resultados dos métodos utilizados para prevenção das aderências pericárdicas.</abstract><doi>10.1590/S0102-86502009000200002</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0102-8650
ispartof Acta cirúrgica brasileira, 2009-04, Vol.24 (2), p.82-86
issn 0102-8650
0102-8650
language eng
recordid cdi_crossref_primary_10_1590_S0102_86502009000200002
source SciELO
title New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T21%3A47%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=New%20quantitative%20variables%20to%20measure%20postoperative%20pericardial%20adhesions:%20useful%20tools%20in%20experimental%20research&rft.jtitle=Acta%20cir%C3%BArgica%20brasileira&rft.au=Lopes,%20Jackson%20Brand%C3%A3o&rft.date=2009-04-01&rft.volume=24&rft.issue=2&rft.spage=82&rft.epage=86&rft.pages=82-86&rft.issn=0102-8650&rft.eissn=0102-8650&rft_id=info:doi/10.1590/S0102-86502009000200002&rft_dat=%3Ccrossref%3E10_1590_S0102_86502009000200002%3C/crossref%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c434t-58a7613928769febed8ecb92ea0f2f3f81669309aa89b24f8204cc12660b1e2d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true