Inflammation markers in healthy and periodontitis patients: a preliminary data screening

Advances in diagnostic research are moving towards methods whereby the periodontal risk can be identified and quantified by objective measures using biomarkers. Patients with periodontitis may have elevated circulating levels of specific inflammatory markers that can be correlated to the severity of...

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Published in:Brazilian dental journal 2008, Vol.19 (1), p.3-8
Main Authors: Queiroz, Adriana Corrêa de, Taba Jr, Mario, O'Connell, Patrícia Aquino, Nóbrega, Priscila Brasil da, Costa, Priscila Paganini, Kawata, Viviane Keiko dos Santos, Trevisan, Glauce Lunardelli, Novaes Jr, Arthur Belém, Souza, Sergio Luís Scombatti de, Palioto, Daniela Bazan, Grisi, Márcio Fernando de Moraes
Format: Article
Language:English
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Summary:Advances in diagnostic research are moving towards methods whereby the periodontal risk can be identified and quantified by objective measures using biomarkers. Patients with periodontitis may have elevated circulating levels of specific inflammatory markers that can be correlated to the severity of the disease. The purpose of this study was to evaluate whether differences in the serum levels of inflammatory biomarkers are differentially expressed in healthy and periodontitis patients. Twenty-five patients (8 healthy patients and 17 chronic periodontitis patients) were enrolled in the study. A 15 mL blood sample was used for identification of the inflammatory markers, with a human inflammatory flow cytometry multiplex assay. Among 24 assessed cytokines, only 3 (RANTES, MIG and Eotaxin) were statistically different between groups (p
ISSN:0103-6440
0103-6440
DOI:10.1590/S0103-64402008000100001