Highly sensitive electrochemical sensing platform for the detection of L-dopa based on electropolymerizing glutathione disulfide and multi-walled carbon nanotube-modified electrodes

A facile sensing platform for the detection of L-dopa has been developed by electropolymerizing glutathione disulfide (PGSSG) on the surface of glass carbon electrodes (GCE) which were modified by multi-walled carbon nanotubes (MWCNTs). The electrochemical behaviour of the proposed electrodes were i...

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Bibliographic Details
Published in:South African journal of chemistry 2018-01, Vol.71 (1), p.182-187
Main Authors: Fu, Yingzi, Song, Jinyi, Zhu, Shu, Ran, Peiyao, Ma, Jiao, Yang, Chengcheng
Format: Article
Language:English
Subjects:
Electrochemical determination
Electropolymerization
Glutathione disulfide
L-dopa
Multi-walled carbon nanotubes
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Summary:A facile sensing platform for the detection of L-dopa has been developed by electropolymerizing glutathione disulfide (PGSSG) on the surface of glass carbon electrodes (GCE) which were modified by multi-walled carbon nanotubes (MWCNTs). The electrochemical behaviour of the proposed electrodes were investigated via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The morphology of the PGSSG and PGSSG/MWCNTs were characterized by scanning electron microscopy (SEM). Under the optimized experimental conditions, the sensing platform showed the linear response to L-Dopa in a range from 1.0 × 10–6 to 1.2 × 10–3 M with a detection limit of 3.3 × 10–7 M (S/N = 3). Moreover, with the merits of high sensitivity and selectivity, good stability and reproducibility, the sensor was successfully applied for the determination of L-dopa in a real sample.
ISSN:0379-4350
1996-840X
DOI:10.17159/0379-4350/2018/v71a24