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A critique on cell signallings involve in colorectal cancer

Colorectal carcinogenesis (CRC) is a significant health issue in developing countries. It ranks as the third most common outcome of cancer death. New drugs are required to lower the prevalence of this ailment despite a multitude of therapeutic choices. As CRC develops, several signaling pathways pat...

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Bibliographic Details
Published in:Indian journal of clinical anatomy and physiology 2022-10, Vol.9 (3), p.161-165
Main Authors: Singh, Seema, Abdulsalam, Raza, Tahseen
Format: Article
Language:English
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Summary:Colorectal carcinogenesis (CRC) is a significant health issue in developing countries. It ranks as the third most common outcome of cancer death. New drugs are required to lower the prevalence of this ailment despite a multitude of therapeutic choices. As CRC develops, several signaling pathways pathways are activated. Among the important signaling pathways are the p53, Delta-Notch, Wnt/-catenin, Salvador-Warts-Hippo (SWH), and Kelch-like ECH assocd protein 1 pathways. This paper summarises the aetiology of CRC as well as the related death of cells and cell signal transduction pathways.
ISSN:2394-2118
2394-2126
DOI:10.18231/j.ijcap.2022.035