Electrochemical Determination of Gliclazide on Magnetic Core-Shell Fe3O4@SiO2 Functionalized Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode

The report covers the construction of a novel modified glassy carbon electrode (GCE), using magnetic core-shell Fe3O4@SiO2 and multi-walled carbon nanotubes (MWCNTs). The resulting device was then tested as a tool for the sensitive and selective analysis of traces of gliclazide (GLZ). The effects of...

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Bibliographic Details
Published in:International journal of electrochemical science 2017-10, Vol.12 (10), p.8868-8877
Main Authors: Ganjali, Mohammad Reza, Salimi, Hadiseh, Tajik, Somayeh, Beitollahi, Hadi, Badiei, Alireza, Mohammadi Ziarani, Ghodsi
Format: Article
Language:English
Subjects:
Glassy carbon electrode
Gliclazide
Magnetic core-shell Fe3O4@SiO2/MWCNT nanocomposite
Voltammetry
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Summary:The report covers the construction of a novel modified glassy carbon electrode (GCE), using magnetic core-shell Fe3O4@SiO2 and multi-walled carbon nanotubes (MWCNTs). The resulting device was then tested as a tool for the sensitive and selective analysis of traces of gliclazide (GLZ). The effects of different parameters, i.e. pH of the test solution, and the scan rate applied during the electrochemical determination process on the performance of the resulting electrode were also assessed. The results obtained under the optimal conditions showed the response of the electrode to gliclazide to be linear over a rather wide range of 5.0 × 10−6 to 8.0 × 10−4 M, and a detection limit of as low as 2.1 × 10− 6 M (pH=7.0). The proposed sensor was successfully applied for the determination of gliclazide in real samples.
ISSN:1452-3981
1452-3981
DOI:10.20964/2017.10.63