Ultrasensitive and Indirect Electrochemical Detection of Sulfamethoxazole Using Ag2O @ MWCNTs Nanocomposites Modified Glassy Carbon Electrode

• Published in: International journal of electrochemical science 2020-08, Vol.15 (8), p.7610-7623
• Main Authors: Zhang, Wenhao, Li, Rui, Zhu, Mingfang, Zhou, Wen, Lai, Mushen, Liang, Huanru, Zhu, Rongkun, Ye, Hongqing
• Format: Article
• Language: English
• Subjects: Ag2O@MWCNTs nanocomposites; Differential pulse voltammetry; Sulfamethoxazole; Ultrosensitive and indirect detection
• ISSN: 1452-3981; 1452-3981
• DOI: 10.20964/2020.08.74

The Ag2O @ MWCNTs nanocomposites material was prepared via simple, one-step situ precipitation method using conventional reagent. The obtained Ag2O @ MWCNTs was structurally characterized by scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR) and ultraviolet and visible spectrophotometry (UV–Vis). The functional GCE with Ag2O @ MWCNTs exhibits good electrochemical performances with a pair of quasi-reversible redox peak. While sulfamethoxazole (SMX) can interact with Ag(I) to form Ag-SMX complex, which makes the concentrations of silver ion involved in the redox reaction decreased, thus reducing the redox peak of Ag2O @ MWCNTs composites. The decreased oxidation peak current is found to be linear with the SMX concentrations from 0.02–100 nM and the detection limit was 4.06×10-12 M (S/N=3) by using DPV method. Furthermore, the proposed method demonstrated excellent selectivity, repeatability and reproducibility, and can be successfully applied for the SMX analysis in human serum.