CHRONIC TOXICITY AND HEPATOCARCINOGENICITY OF (+) RUGULOSIN, AN ANTHRAQUINOID MYCOTOXIN FROM PENICILLIUM SPECIES : PRELIMINARY SURVEYS IN MICE

Long-term feeding experiments revealed chronic hepatocellular injury as well as hepatocarcinogenicity of (+) rugulosin in mice.

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Bibliographic Details
Published in:Journal of toxicological sciences 1980/11/15, Vol.5(4), pp.295-302
Main Authors: UENO, Yoshio, SATO, Norio, ITO, Teruo, UENO, Ikuko, ENOMOTO, Makoto, TSUNODA, Hiroshi
Format: Article
Language:English
Subjects:
Animals
Anthraquinones - toxicity
Carcinogens
hepatocarcinogenicity
Hyperplasia
Liver - drug effects
Liver - pathology
Liver Neoplasms, Experimental - chemically induced
Liver Neoplasms, Experimental - pathology
Male
Mice
Mycotoxins - toxicity
Penicillium
Time Factors
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Description
Summary:Long-term feeding experiments revealed chronic hepatocellular injury as well as hepatocarcinogenicity of (+) rugulosin in mice.
ISSN:0388-1350
1880-3989
DOI:10.2131/jts.5.295