TRITERPENES FROM CERIOPS DECANDRA (GRIFF.) W. THEOB

  Objective: To isolate and identify the chemical constituents of Ceriops decandra. Methods: The chemical constituents of C. decandra (Griff.) W. Theob. were isolated by silica gel chromatography. The structures of the isolated compounds were identified by nuclear magnetic resonance (NMR) spectrosco...

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Bibliographic Details
Published in:Asian journal of pharmaceutical and clinical research 2017-11, Vol.10 (11), p.244
Main Authors: Perez, Judy, Shen, Chien-chang, Ragasa, Consolacion Y
Format: Article
Language:English
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Summary:  Objective: To isolate and identify the chemical constituents of Ceriops decandra. Methods: The chemical constituents of C. decandra (Griff.) W. Theob. were isolated by silica gel chromatography. The structures of the isolated compounds were identified by nuclear magnetic resonance (NMR) spectroscopy.Results: Chemical investigation of the dichloromethane extracts of the leaves of C. decandra has led to the isolation of 3β-E-coumaroylbetulinic acid (1), lupeol fatty acid esters (2), betulonic acid (3), betulin (4), betulinic acid (5), lupeol (6), lupenone (7), and a mixture of 3β-E-feruloyllupeol (8) and 3β-Z-feruloyllupeol (9), and chlorophyll a (10). The structures of 1-10 were identified by comparison of their NMR data with literature data.Conclusion: To the best of our knowledge, this is the first report on the isolation of 1-3 from C. decandra. Literature search revealed that the triterpenes isolated from C. decandra exhibited anticancer properties.
ISSN:0974-2441
0974-2441
DOI:10.22159/ajpcr.2017.v10i11.19461