COMPARATIVE ESTIMATION OF SALIVARY TOTAL ANTIOXIDANT CAPACITY IN PERIODONTAL HEALTH AND CHRONIC PERIODONTITIS - A PILOT STUDY

Objective: Gram-negative bacteria provoke polymorphonuclear leukocyte (PMN) to release reactive oxygen species in chronic periodontitis (CP). Inability to maintain a balance between oxidative stress and antioxidant levels makes patients more susceptible to periodontal disease. The present study aims...

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Bibliographic Details
Published in:Asian journal of pharmaceutical and clinical research 2018-10, Vol.11 (10), p.523
Main Authors: Raghavendra, U, Rao, Anupama, D'suoza, Jyothi, Pai, Vinita Ramanath, Nair, Sindhu, Kumar, Vijaya, Kalal, Bhuvanesh Sukhlal
Format: Article
Language:English
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Summary:Objective: Gram-negative bacteria provoke polymorphonuclear leukocyte (PMN) to release reactive oxygen species in chronic periodontitis (CP). Inability to maintain a balance between oxidative stress and antioxidant levels makes patients more susceptible to periodontal disease. The present study aims to estimate and compare salivary total antioxidant capacity (TAOC) in subjects with clinically healthy periodontium and patients with CP.Methods: After fulfilling the selection criteria, a total of 20 subjects (10 with clinically healthy periodontium and 10 with CP) were subjected to unstimulated salivary sample collection for biochemical estimation of TAOC by spectrophotometric assay using Kovacevic method. Analysis of data was done with unpaired student t-test, using SPSS version 22 statistical program.Results: Salivary TAOC was significantly higher in subjects with clinically healthy periodontium compared to CP patients. It was statistically significant (p
ISSN:0974-2441
0974-2441
DOI:10.22159/ajpcr.2018.v11i10.28409