ASSESSMENT OF INFLAMMATORY STATUS IN METABOLIC SYNDROME

• Published in: Asian journal of pharmaceutical and clinical research 2018-07, Vol.11 (7), p.259
• Main Authors: Krishna, Nivesh, Roy, Anitha, G, Savitha
• Format: Article
• Language: English
• ISSN: 0974-2441; 0974-2441
• DOI: 10.22159/ajpcr.2018.v11i7.25744

Objective: The aim of the present study was to assess the level of inflammation in metabolic syndrome (MetS) individuals by estimating C-reactive protein (CRP) in the individuals.Methods: A total of 60 subjects were selected from those attending the outpatient department of a private hospital and divided into two groups (n=30): Group 1 - healthy individuals and Group 2 - individuals with MetS. Informed consent was obtained from the subjects before sample collection. 5 ml of fasting venous blood was collected and centrifuged at 3000 rpm to separate serum, and then, it was analyzed for fasting blood sugar (FBS) by glucose oxidase-peroxidase method, serum triglycerides (TGL) by colorimetric enzymatic method, and serum CRP by Turbilatex method using ERBA CHEM 5 plus analyzer.Results: Mean body mass index level in control and MetS group is 22.73±2.14 and 35.53±3.57, respectively. Mean FBS levels in the control group and MetS group are 85.6±11.59 and 115.67±24.52, respectively. Mean TGL levels in the normal control group and MetS group are 105.63±30.26 and 181.07±47.76, respectively. Mean CRP levels in the normal control and MetS group are 3.17±1.22 and 8.34±2.48, respectively.Conclusion: CRP level positively correlated with MetS. Evaluation of CRP can be used as a surrogate marker to assess the inflammatory status of MetS individuals.