IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE

Objective: The aim of the present investigation was to determine the in vitro antioxidant and anticancer activity of the ethanol extract of Ulva lactuca L. Methods: The present study was to investigate the antioxidant and anticancer activity of U. lactuca L. The extract of U. lactuca L. was extracte...

Full description

Saved in:
Bibliographic Details
Published in:Asian journal of pharmaceutical and clinical research 2019-03, p.75-78
Main Authors: CHIDAMBARARAJAN P, KEERTHANA V, PRIYADHARSHINI K, SAKTHIVEL B
Format: Article
Language:English
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c1025-ac85ea9c2aa42b01dd53ff38e6f9e8d6a5cacf3a36a6c513748fcd11ff7058243
cites
container_end_page 78
container_issue
container_start_page 75
container_title Asian journal of pharmaceutical and clinical research
container_volume
creator CHIDAMBARARAJAN P
KEERTHANA V
PRIYADHARSHINI K
SAKTHIVEL B
description Objective: The aim of the present investigation was to determine the in vitro antioxidant and anticancer activity of the ethanol extract of Ulva lactuca L. Methods: The present study was to investigate the antioxidant and anticancer activity of U. lactuca L. The extract of U. lactuca L. was extracted by ethanol and subject to analysis. An in vitro antioxidant activity of the ethanol extract of U. lactuca L. was performed by 1, 1-diphenyl-2-picrylhydrazyl free radical scavenging assay. Simultaneously anticancer activity was also performed using blood cancer (MOLT-3) cell line, and the species showed a strong selective cell proliferation inhibition of the cancer cell line. Results: The scavenging activity was measured and determined to be 78.5%. This might be due to high polyphenolic compounds and flavonoid contents of the extract, which showed maximum growth inhibition of 74.4%. Conclusion: Thus, the study concludes that the constituents of seaweeds can act as potent in treating various diseases and can be used as an alternative for therapeutic treatment.
doi_str_mv 10.22159/ajpcr.2019.v12i5.29825
format article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_22159_ajpcr_2019_v12i5_29825</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_22159_ajpcr_2019_v12i5_29825</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1025-ac85ea9c2aa42b01dd53ff38e6f9e8d6a5cacf3a36a6c513748fcd11ff7058243</originalsourceid><addsrcrecordid>eNpNkN1KxDAQRoMouOg-g3mB1kx-muayZLtrILawtotehZg2sIvi0oLg2xurF87N-WYYvouD0B2QnFIQ6t6fzmHKKQGVfwI9ipyqkooLtCJK8oxyDpf_8jVaz_OJpGFKSJAr1JsGH0y3b3HVdKZ9NpvElDfLrqtG13tc6c6kpxfcbnFvDxW26dLrxLx_Ms0OP7a2yxjWtbXYmqa-RVfRv83j-o83qN_WnX7IbLtLpTYLQKjIfCjF6FWg3nP6SmAYBIuRlWMR1VgOhRfBh8g8K3wRBDDJyxgGgBglESXl7AbJ394wfczzNEZ3no7vfvpyQNwiyC2C3I8gtwhyiyD2DY8rVBY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE</title><source>Free Full-Text Journals in Chemistry</source><creator>CHIDAMBARARAJAN P ; KEERTHANA V ; PRIYADHARSHINI K ; SAKTHIVEL B</creator><creatorcontrib>CHIDAMBARARAJAN P ; KEERTHANA V ; PRIYADHARSHINI K ; SAKTHIVEL B</creatorcontrib><description>Objective: The aim of the present investigation was to determine the in vitro antioxidant and anticancer activity of the ethanol extract of Ulva lactuca L. Methods: The present study was to investigate the antioxidant and anticancer activity of U. lactuca L. The extract of U. lactuca L. was extracted by ethanol and subject to analysis. An in vitro antioxidant activity of the ethanol extract of U. lactuca L. was performed by 1, 1-diphenyl-2-picrylhydrazyl free radical scavenging assay. Simultaneously anticancer activity was also performed using blood cancer (MOLT-3) cell line, and the species showed a strong selective cell proliferation inhibition of the cancer cell line. Results: The scavenging activity was measured and determined to be 78.5%. This might be due to high polyphenolic compounds and flavonoid contents of the extract, which showed maximum growth inhibition of 74.4%. Conclusion: Thus, the study concludes that the constituents of seaweeds can act as potent in treating various diseases and can be used as an alternative for therapeutic treatment.</description><identifier>ISSN: 0974-2441</identifier><identifier>EISSN: 0974-2441</identifier><identifier>DOI: 10.22159/ajpcr.2019.v12i5.29825</identifier><language>eng</language><ispartof>Asian journal of pharmaceutical and clinical research, 2019-03, p.75-78</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1025-ac85ea9c2aa42b01dd53ff38e6f9e8d6a5cacf3a36a6c513748fcd11ff7058243</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>CHIDAMBARARAJAN P</creatorcontrib><creatorcontrib>KEERTHANA V</creatorcontrib><creatorcontrib>PRIYADHARSHINI K</creatorcontrib><creatorcontrib>SAKTHIVEL B</creatorcontrib><title>IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE</title><title>Asian journal of pharmaceutical and clinical research</title><description>Objective: The aim of the present investigation was to determine the in vitro antioxidant and anticancer activity of the ethanol extract of Ulva lactuca L. Methods: The present study was to investigate the antioxidant and anticancer activity of U. lactuca L. The extract of U. lactuca L. was extracted by ethanol and subject to analysis. An in vitro antioxidant activity of the ethanol extract of U. lactuca L. was performed by 1, 1-diphenyl-2-picrylhydrazyl free radical scavenging assay. Simultaneously anticancer activity was also performed using blood cancer (MOLT-3) cell line, and the species showed a strong selective cell proliferation inhibition of the cancer cell line. Results: The scavenging activity was measured and determined to be 78.5%. This might be due to high polyphenolic compounds and flavonoid contents of the extract, which showed maximum growth inhibition of 74.4%. Conclusion: Thus, the study concludes that the constituents of seaweeds can act as potent in treating various diseases and can be used as an alternative for therapeutic treatment.</description><issn>0974-2441</issn><issn>0974-2441</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpNkN1KxDAQRoMouOg-g3mB1kx-muayZLtrILawtotehZg2sIvi0oLg2xurF87N-WYYvouD0B2QnFIQ6t6fzmHKKQGVfwI9ipyqkooLtCJK8oxyDpf_8jVaz_OJpGFKSJAr1JsGH0y3b3HVdKZ9NpvElDfLrqtG13tc6c6kpxfcbnFvDxW26dLrxLx_Ms0OP7a2yxjWtbXYmqa-RVfRv83j-o83qN_WnX7IbLtLpTYLQKjIfCjF6FWg3nP6SmAYBIuRlWMR1VgOhRfBh8g8K3wRBDDJyxgGgBglESXl7AbJ394wfczzNEZ3no7vfvpyQNwiyC2C3I8gtwhyiyD2DY8rVBY</recordid><startdate>20190318</startdate><enddate>20190318</enddate><creator>CHIDAMBARARAJAN P</creator><creator>KEERTHANA V</creator><creator>PRIYADHARSHINI K</creator><creator>SAKTHIVEL B</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20190318</creationdate><title>IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE</title><author>CHIDAMBARARAJAN P ; KEERTHANA V ; PRIYADHARSHINI K ; SAKTHIVEL B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1025-ac85ea9c2aa42b01dd53ff38e6f9e8d6a5cacf3a36a6c513748fcd11ff7058243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><toplevel>online_resources</toplevel><creatorcontrib>CHIDAMBARARAJAN P</creatorcontrib><creatorcontrib>KEERTHANA V</creatorcontrib><creatorcontrib>PRIYADHARSHINI K</creatorcontrib><creatorcontrib>SAKTHIVEL B</creatorcontrib><collection>CrossRef</collection><jtitle>Asian journal of pharmaceutical and clinical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CHIDAMBARARAJAN P</au><au>KEERTHANA V</au><au>PRIYADHARSHINI K</au><au>SAKTHIVEL B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE</atitle><jtitle>Asian journal of pharmaceutical and clinical research</jtitle><date>2019-03-18</date><risdate>2019</risdate><spage>75</spage><epage>78</epage><pages>75-78</pages><issn>0974-2441</issn><eissn>0974-2441</eissn><abstract>Objective: The aim of the present investigation was to determine the in vitro antioxidant and anticancer activity of the ethanol extract of Ulva lactuca L. Methods: The present study was to investigate the antioxidant and anticancer activity of U. lactuca L. The extract of U. lactuca L. was extracted by ethanol and subject to analysis. An in vitro antioxidant activity of the ethanol extract of U. lactuca L. was performed by 1, 1-diphenyl-2-picrylhydrazyl free radical scavenging assay. Simultaneously anticancer activity was also performed using blood cancer (MOLT-3) cell line, and the species showed a strong selective cell proliferation inhibition of the cancer cell line. Results: The scavenging activity was measured and determined to be 78.5%. This might be due to high polyphenolic compounds and flavonoid contents of the extract, which showed maximum growth inhibition of 74.4%. Conclusion: Thus, the study concludes that the constituents of seaweeds can act as potent in treating various diseases and can be used as an alternative for therapeutic treatment.</abstract><doi>10.22159/ajpcr.2019.v12i5.29825</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0974-2441
ispartof Asian journal of pharmaceutical and clinical research, 2019-03, p.75-78
issn 0974-2441
0974-2441
language eng
recordid cdi_crossref_primary_10_22159_ajpcr_2019_v12i5_29825
source Free Full-Text Journals in Chemistry
title IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF ULVA LACTUCA L.USING MOLT-3 CELL LINE
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T15%3A09%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=IN%20VITRO%20ANTIOXIDANT%20AND%20ANTICANCER%20ACTIVITY%20OF%20ULVA%20LACTUCA%20L.USING%20MOLT-3%20CELL%20LINE&rft.jtitle=Asian%20journal%20of%20pharmaceutical%20and%20clinical%20research&rft.au=CHIDAMBARARAJAN%20P&rft.date=2019-03-18&rft.spage=75&rft.epage=78&rft.pages=75-78&rft.issn=0974-2441&rft.eissn=0974-2441&rft_id=info:doi/10.22159/ajpcr.2019.v12i5.29825&rft_dat=%3Ccrossref%3E10_22159_ajpcr_2019_v12i5_29825%3C/crossref%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c1025-ac85ea9c2aa42b01dd53ff38e6f9e8d6a5cacf3a36a6c513748fcd11ff7058243%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true