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Ultrasound-guided 5% dextrose prolotherapy versus corticosteroid injection in carpal tunnel syndrome: a randomized, controlled clinical trial

The main assessment of this study is to analyze the efficiency of ultrasound-guided dextrose prolotherapy against corticosteroid injections for the treatment of carpal tunnel syndrome.  A total of 54 patients with carpal tunnel syndrome were included. Patients who were assigned into the prolotherapy...

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Bibliographic Details
Published in:Pain management (London) 2022-09, Vol.12 (6), p.687-697
Main Authors: Babaei-Ghazani, Arash, Moradnia, Sara, Azar, Maziar, Forogh, Bijan, Ahadi, Tannaz, Chaibakhsh, Samira, Khodabandeh, Mehrdad, Eftekharsadat, Bina
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Language:English
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Summary:The main assessment of this study is to analyze the efficiency of ultrasound-guided dextrose prolotherapy against corticosteroid injections for the treatment of carpal tunnel syndrome.  A total of 54 patients with carpal tunnel syndrome were included. Patients who were assigned into the prolotherapy group were injected with 5cc 5% dextrose water under ultrasound guidance. Patients in the corticosteroid group received ultrasound-guided 1 ml triamcinolone 40 mg/ml injection. The inter-group analysis revealed that dextrose prolotherapy has a similar efficacy as corticosteroid for improving pain intensity, functional limitation in daily life, electrophysiologic parameters and ultrasonographic outcomes. No remarkable difference was found between the two treatments until 3 months of follow-up. Dextrose 5% has similar efficacy as triamcinolone for improving pain intensity, functional limitation in daily life, electrophysiologic parameters and ultrasonographic outcomes.
ISSN:1758-1869
1758-1877
DOI:10.2217/pmt-2022-0018