A Within-Strain Difference in Radiation Sensitivity in the RFM Mouse

Two sublines of mice from an inbred RFM colony were shown to have different sensitivities when exposed to continuous low dose-rate γ-ray exposure. The sublines, selected by H-2 testing into either ${\rm H}-2^{{\rm f}}$ or ${\rm H}-2^{{\rm k}}$ lines, appear to reveal the influence of a radiation res...

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Bibliographic Details
Published in:Radiation research 1969-10, Vol.40 (1), p.37-45
Main Authors: Spalding, J. F., Popp, Diana M., Popp, R. A.
Format: Article
Language:English
Subjects:
Alleles
Animal genetics
Animals
Bone marrow
Bone Marrow - radiation effects
Cobalt Isotopes
Erythrocyte Count
Genetic loci
Genotype
Hematocrit
Inbred strains
Inbreeding
Ley lines
Mice
Radiation dosage
Radiation Genetics
Radiation Injuries, Experimental - mortality
Radiation tolerance
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Summary:Two sublines of mice from an inbred RFM colony were shown to have different sensitivities when exposed to continuous low dose-rate γ-ray exposure. The sublines, selected by H-2 testing into either ${\rm H}-2^{{\rm f}}$ or ${\rm H}-2^{{\rm k}}$ lines, appear to reveal the influence of a radiation resistance factor associated with or closely linked to the H-2 locus.
ISSN:0033-7587
1938-5404
DOI:10.2307/3572981